SCHEMBL714350

SCHEMBL714350

CC(C)N(C(C)C)P(OCCC#N)OCCCCCCNC(=O)C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
EPHX1 P07099 1/20 0.42
ALDH1A1 P00352 1/20 0.41
POLB P06746 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CA14 Q9ULX7 2/20 0.38
CA3 P07451 2/20 0.38
CA5A P35218 2/20 0.38
CA5B Q9Y2D0 2/20 0.38
CA12 O43570 1/20 0.38
CA2 P00918 1/20 0.38
CA4 P22748 1/20 0.38
CA6 P23280 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6045455 0.96 ALDH1A1 (0.41) MEN1KMT2AEPHX1ALDH1A1POLB
SCHEMBL27052880 0.94 MEN1 (0.38) MEN1KMT2AEPHX1ALDH1A1POLB
SCHEMBL12500466 0.86 MEN1 (0.34) MEN1KMT2AEPHX1ALDH1A1POLB
SCHEMBL14538819 0.86 EPHX1 (0.49) MEN1KMT2AEPHX1ALDH1A1POLB
SCHEMBL18349839 0.85 EPHX1 (0.36) MEN1KMT2AEPHX1ALDH1A1POLB
SCHEMBL14538977 0.84 EPHX1 (0.47) MEN1KMT2AEPHX1ALDH1A1POLB
SCHEMBL6766479 0.84 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2
SCHEMBL27052622 0.83 EPHX1 (0.44) EPHX1SMN1; SMN2
SCHEMBL27097854 0.83 EPHX1 (0.44) EPHX1SMN1; SMN2
SCHEMBL27055720 0.83 EPHX1 (0.44) EPHX1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1945750-A2 MICROARRAY HAVING A BASE CLEAVABLE SUCINATE LINKER Combimatrix Corporation (US) 2008-07-23 EP claimed
WO-2007040469-A2 CHLOROQUINE COUPLED COMPOSITIONS AND METHODS FOR THEIR SYNTHESIS KOSAK KEN M (US) 2007-04-12 WO claimed
WO-2007035500-A2 MICROARRAY HAVING A BASE CLEAVABLE SUCCINATE LINKER COMBIMATRIX CORPORATION (US) 2007-03-29 WO claimed
US-12606817-B2 Methods of creating and screening DNA-encoded libraries X-CHEM, INC. (US) 2026-04-21 US disclosed
EP-4547871-B1 A METHOD, USES, SYSTEM AND KIT FOR DETECTING A HUMAN PAPILLOMAVIRUS GENOTYPE ASSOCIATED WITH DEVELOPMENT OF CERVICAL, ORAL OR ANOGENITAL CANCER IN A SUBJECT AND FOR DETERMINING THE GENOTYPE OR GENOTYPES THEREOF VITRO S A (ES) 2026-01-14 EP disclosed
US-20260002224-A1 A METHOD, USES, SYSTEM AND KIT FOR DETECTING A HUMAN PAPILLOMAVIRUS GENOTYPE ASSOCIATED WITH DEVELOPMENT OF CERVICAL, ORAL OR ANOGENITAL CANCER IN A SUBJECT AND FOR DETERMINING THE GENOTYPE OR GENOTYPES THEREOF VITRO, S.A. (ES) 2026-01-01 US disclosed
US-20250361399-A1 FLUORESCENT DYES WITH LARGE STOKES SHIFT ROCHE MOLECULAR SYSTEMS INC (US) 2025-11-27 US disclosed
US-20250325675-A1 APTAMER, CONJUGATE, COMPOSITION, METHOD FOR PREPARING SAME, AND USE THEREOF Suzhou Ribo Life Science Co., Ltd. (CN) 2025-10-23 US disclosed
US-20250320488-A1 METHODS OF PREPARING OLIGONUCLEOTIDE-DIRECTED COMBINATORIAL LIBRARIES INSITRO, INC. (US) 2025-10-16 US disclosed
US-12421516-B2 Antisense oligomers targeting PCSK9 ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) 2025-09-23 US disclosed
US-20250269040-A1 CONJUGATE, PHARMACEUTICAL COMPOSITION COMPRISING SAME, METHOD FOR PREPARING SAME, AND USE THEREOF Suzhou Ribo Life Science Co., Ltd. (CN) 2025-08-28 US disclosed
US-6228592-B1 MONITORING TARGET NUCLEOTIDE SEQUENCES IN SAMPLE; INSERT PROBES INTO SOLUTION, ALLOW HYBRIDIZATION TO OCCUR, MONITOR ADJUSTMENT IN FLUORESCENCE, ADJUSTMENT IN FLUORESCENCE INDICATES PRESENCE OF NUCLEIC ACIDS LABORATORY OF MOLECULAR BIOPHOTONICS (JP) 2001-05-08 US disclosed
US-6180347-B1 DETECTING ACTIVATION AND TERMINATION OF TRANSCRIPTION; TRANSCRIBE SEQUENCES USING OLIGONUCLEOTIDE PROBES, MEASURING FLUORESCENCE OF PROBES AND EVALUATING ADJUSTMENT IN FLUORESCENCE LABORATORY OF MOLECULAR BIOPHOTONICS (JP) 2001-01-30 US disclosed
US-6172208-B1 DIAGNOSTIC PROBE; DNA, RNA, PEPTIDE, AND PROTEIN CONJUGATES; GENETIC ENGINEERING GENZYME CORPORATION 2001-01-09 US disclosed
EP-1052293-A1 Nucleic acid detection in cytoplasm Laboratory of Molecular Biophotonics (JP) 2000-11-15 EP disclosed
EP-0965635-A1 METHOD FOR MONITORING TRANSCRIPTIONAL SYNTHESIS OF RNA AND APPARATUS THEREFOR Laboratory of Molecular Biophotonics (JP) 1999-12-22 EP disclosed
US-6004826-A Repair-mediated process for amplifying and detecting nucleic acid sequences Segev, David 1999-12-21 US disclosed
WO-1995019449-A1 POPULATIONS OF NON-ADJACENT HYBRIDIZATION PROBES APROGENEX, INC. (US) 1995-07-20 WO disclosed
WO-1995019450-A1 BACKGROUND-REDUCING COMPOUNDS FOR PROBE-MEDIATED IN-SITU FLUORIMETRIC ASSAYS APROGENEX, INC. (US) 1995-07-20 WO disclosed
WO-1994001448-A1 OLIGONUCLEOTIDES MODIFIED WITH CONJUGATE GROUPS PHARMAGENICS, INC. (US) 1994-01-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12421516-B2 Antisense oligomers targeting PCSK9 PCSK9, PCSK7, PCSK6 MEN1 1761/4885KMT2A 1710/4885EPHX1 2111/4885
US-20250325675-A1 APTAMER, CONJUGATE, COMPOSITION, METHOD FOR PREPARING SAME, AND USE THEREOF MCTS1, RNASE1, ASGR1 MEN1 265/4885KMT2A 2008/4885EPHX1 2779/4885
US-20260002224-A1 A METHOD, USES, SYSTEM AND KIT FOR DETECTING A HUMAN PAPILLOMAVIRUS GENOTYPE ASSOCIATED WITH DEVELOPMENT OF CERVICAL, ORAL OR ANOGENITAL CANCER IN A SUBJECT AND FOR DETERMINING THE GENOTYPE OR GENOTYPES THEREOF TSG101, MKI67, DHX35 MEN1 3252/4885KMT2A 2259/4885EPHX1 250/4885
US-20250269040-A1 CONJUGATE, PHARMACEUTICAL COMPOSITION COMPRISING SAME, METHOD FOR PREPARING SAME, AND USE THEREOF RNASE1, MCTS1, ATIC MEN1 221/4885KMT2A 1437/4885EPHX1 2812/4885
US-12606817-B2 Methods of creating and screening DNA-encoded libraries PCNA, DNA2, POLM MEN1 2986/4885KMT2A 3602/4885EPHX1 2921/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.