SCHEMBL676655

SCHEMBL676655

CNc1ccc(C2(c3ccc(NC(=O)c4cccc(C(C)=O)c4)c(O)c3)c3ccccc3-c3ccccc32)cc1O

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
CREBBP Q92793 4/20 0.39
POLB P06746 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
KMT2A Q03164 6/20 0.39
RAB9A P51151 3/20 0.38
NPC1 O15118 2/20 0.38
MEN1 O00255 5/20 0.38
PYGM P11217 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
ABCB1 P08183 1/20 0.37
ABCC1 P33527 1/20 0.37
PKM P14618 1/20 0.36
GFER P55789 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL677406 0.90 ESR1 (0.42) ESR1ESR2POLBKMT2ARAB9A
SCHEMBL1108319 0.89 ESR1 (0.44) ESR1ESR2CREBBPPOLBTDP1
SCHEMBL676672 0.82 KMT2A (0.46) ESR1ESR2POLBTDP1KMT2A
SCHEMBL13967732 0.80 KMT2A (0.53) POLBTDP1KMT2ARAB9ANPC1
SCHEMBL13520186 0.79 NPC1 (0.53) CREBBPPOLBKMT2ARAB9ANPC1
SCHEMBL14025194 0.76 ESR1 (0.35) ESR1ESR2POLBKMT2ARAB9A
SCHEMBL17991076 0.76 KMT2A (0.56) ESR1ESR2POLBKMT2ARAB9A
SCHEMBL10030653 0.75 KMT2A (0.51) CREBBPPOLBKMT2ARAB9ANPC1
SCHEMBL1108311 0.75 CREBBP (0.49) CREBBPPOLBKMT2ARAB9ANPC1
SCHEMBL13929676 0.75 PDK2 (0.50) ESR1ESR2POLBTDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1995271-B1 EPOXY RESIN CURABLE COMPOSITION FOR PREPREG ADEKA CORP (JP) 2013-07-24 EP disclosed
US-7906213-B2 Epoxy resin curable composition for prepreg ADEKA CORPORATION (JP) 2011-03-15 US disclosed
US-20090030147-A1 Epoxy Resin Curable Composition For Prepreg ADEKA CORPORATION (JP) 2009-01-29 US disclosed