Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 17/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.41 |
| ▸ | PRKACA | P17612 | 2/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.41 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.41 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.41 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.41 |
| ▸ | PRKCB | P05771 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.41 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.41 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | LYN | P07948 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6763950 | 0.96 | MAPK14 (0.42) | MAPK14PRKD3MAP4K4PRKACACSNK1A1 | |
| SCHEMBL6768614 | 0.93 | MAPK14 (0.44) | MAPK14PRKD3MAP4K4PRKACACSNK1A1 | |
| SCHEMBL6769364 | 0.92 | MAPK14 (0.43) | MAPK14PRKD3MAP4K4PRKACACSNK1A1 | |
| SCHEMBL6767235 | 0.90 | MAPK14 (0.41) | MAPK14PRKD3MAP4K4PRKACACSNK1A1 | |
| SCHEMBL6768676 | 0.90 | MAPK14 (0.42) | MAPK14PRKD3MAP4K4PRKACACSNK1A1 | |
| SCHEMBL6768661 | 0.88 | MAPK14 (0.42) | MAPK14PRKD3MAP4K4PRKACACSNK1A1 | |
| SCHEMBL6768641 | 0.87 | ACACB (0.39) | MAPK14PRKD3MAP4K4CSNK1A1CSNK1D | |
| SCHEMBL6768364 | 0.83 | MAPK14 (0.63) | MAPK14BRDTBRD4 | |
| SCHEMBL6766904 | 0.82 | PRKD3 (0.41) | MAPK14PRKD3MAP4K4CSNK1A1CSNK1D | |
| SCHEMBL6766744 | 0.81 | MAPK14 (0.61) | MAPK14MAPK11BRDTMAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677337-B2 | RHEUMATOID ARTHRITIS, OSTEOARTHRITIS, INFLAMMATORY BOWEL DISEASE, CACHEXIA, SEPTIC SHOCK, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | THE PROCTER & GAMBLE COMPANY | 2004-01-13 | — | — | US | claimed |