Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20647004 | 0.89 | GRIK1 (0.51) | MAPTKMT2AMEN1KDM4EHSD17B10 | |
| SCHEMBL6763737 | 0.86 | MAPT (0.50) | MAPTALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL13062695 | 0.84 | MEN1 (0.47) | MAPTALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL6112937 | 0.82 | PTPN1 (0.47) | MAPTGAAKMT2AMEN1SMYD3 | |
| SCHEMBL4194809 | 0.82 | ALDH1A1 (0.58) | MAPTALDH1A1GAAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7034749 | 0.81 | GAA (0.54) | MAPTALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL27735957 | 0.80 | MAPT (0.40) | MAPTALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL1119917 | 0.79 | MAPT (0.57) | MAPTALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL8543066 | 0.79 | KDM4E (0.44) | MAPTALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL6767250 | 0.78 | RAB9A (0.64) | MAPTALDH1A1GAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699880-B1 | STIMULATE MUSCARINIC ACETYLCHOLINE RECEPTORS M4, ANALGESICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| EP-1221443-A1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-07-10 | — | — | EP | disclosed |