SCHEMBL676692

SCHEMBL676692

COc1c(Br)cc(C(C)(C)c2cc(Br)c(OCC3CO3)c(Br)c2)cc1Br

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.50
TSHR P16473 5/20 0.50
TP53 P04637 3/20 0.50
HPGD P15428 3/20 0.50
HIF1A Q16665 3/20 0.50
MAPT P10636 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
CYP1A2 P05177 1/20 0.50
PPARG P37231 1/20 0.50
GLA P06280 1/20 0.39
CYP3A4 P08684 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
PTPN1 P18031 2/20 0.37
PKM P14618 2/20 0.36
TDP1 Q9NUW8 2/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35
CASP1 P29466 1/20 0.35
RECQL P46063 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24605516 0.94 ALDH1A1 (0.48) ALDH1A1TSHRTP53HPGDHIF1A
SCHEMBL1104781 0.94 ALDH1A1 (0.55) ALDH1A1TSHRTP53HPGDHIF1A
SCHEMBL21846072 0.90 ALDH1A1 (0.51) ALDH1A1TSHRTP53HPGDHIF1A
SCHEMBL19852380 0.89 ALDH1A1 (0.48) ALDH1A1TSHRTP53HPGDHIF1A
SCHEMBL16727406 0.89 ALDH1A1 (0.50) ALDH1A1TSHRTP53HPGDHIF1A
SCHEMBL12643938 0.87 TSHR (0.53) ALDH1A1TSHRTP53HPGDHIF1A
SCHEMBL26869214 0.87 ALDH1A1 (0.49) ALDH1A1TSHRTP53HPGDHIF1A
SCHEMBL943782 0.87 TSHR (0.53) ALDH1A1TSHRTP53HPGDHIF1A
SCHEMBL14212723 0.86 ALDH1A1 (0.48) ALDH1A1TSHRTP53HPGDHIF1A
SCHEMBL1262667 0.86 MEN1 (0.64) ALDH1A1TSHRTP53HPGDHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022144881-A1 POLYMERIC FLAME RETARDANTS BROMINE COMPOUNDS LTD. (IL) 2022-07-07 WO disclosed
US-9631144-B2 Flame retardant composition BROMINE COMPOUNDS LTD. (IL) 2017-04-25 US disclosed
US-9315731-B2 High impact polystyrene flame retarded compositions BROMINE COMPOUNDS LTD. (IL) 2016-04-19 US disclosed
US-8991321-B2 Flame retarded compositions BROMINE COMPOUNDS LTD. (IL) 2015-03-31 US disclosed
US-8991321-B2 Flame retarded compositions BROMINE COMPOUNDS LTD. (IL) 2015-03-31 US disclosed
US-20140378565-A1 FLAME RETARDANT COMPOSITION BROMINE COMPOUNDS LTD (IL) 2014-12-25 US disclosed
US-8865783-B2 Flame retardant composition BROMINE COMPOUNDS LTD. (IL) 2014-10-21 US disclosed
US-20140039095-A9 HIGH IMPACT POLYSTYRENE FLAME RETARDED COMPOSITIONS BROMINE COMPOUNDS LTD. (IL) 2014-02-06 US disclosed
US-20130102703-A1 HIGH IMPACT POLYSTYRENE FLAME RETARDED COMPOSITIONS BAR-YAAKOV YOAV (IL) 2013-04-25 US disclosed
US-8067497-B2 Flame-retardant for engineering thermoplastic applications BROMINE COMPOUNDS LTD. (IL) 2011-11-29 US disclosed
US-8067497-B2 Flame-retardant for engineering thermoplastic applications BROMINE COMPOUNDS LTD. (IL) 2011-11-29 US disclosed