Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6767025 | 1.00 | LMNA (0.39) | LMNAHTTSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL6769960 | 0.84 | TSHR (0.36) | LMNAHTTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL6769965 | 0.84 | TSHR (0.36) | LMNAHTTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL6770392 | 0.82 | LMNA (0.41) | LMNAHTTSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL6770391 | 0.82 | LMNA (0.41) | LMNAHTTSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL6771065 | 0.80 | TSHR (0.38) | LMNAHTTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL6771063 | 0.80 | TSHR (0.38) | LMNAHTTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL6770790 | 0.78 | KMT2A (0.38) | LMNAALDH1A1L3MBTL1KMT2ATSHR | |
| SCHEMBL6770791 | 0.78 | KMT2A (0.38) | LMNAALDH1A1L3MBTL1KMT2ATSHR | |
| SCHEMBL6769690 | 0.76 | HTT (0.40) | LMNAHTTSMN1; SMN2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716857-B2 | 1-(3-HYDROCARBYLOXYIMINO-3-(1-ALKYL-1,2,5,6-TETRAHYDROPYRID-3-YL) -ALKYLPYRROLIDIN-2-ONE DERIVATIVES; RECEPTIVITY; ANALGESICS, GLAUCOMA, PSYCHOSIS, SCHIZOPHRENIA, ANXIOLYTIC AGENTS, BIPOLAR DISORDERS; ANTIDEPRESSANTS; SLEEP DISORDERS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2004-04-06 | — | — | US | claimed |
| US-20030119880-A1 | Tetrahydropyridine derivatives acting on muscarinic acetylcholine receptors | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2003-06-26 | — | — | US | claimed |
| US-6716857-B2 | 1-(3-HYDROCARBYLOXYIMINO-3-(1-ALKYL-1,2,5,6-TETRAHYDROPYRID-3-YL) -ALKYLPYRROLIDIN-2-ONE DERIVATIVES; RECEPTIVITY; ANALGESICS, GLAUCOMA, PSYCHOSIS, SCHIZOPHRENIA, ANXIOLYTIC AGENTS, BIPOLAR DISORDERS; ANTIDEPRESSANTS; SLEEP DISORDERS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2004-04-06 | — | — | US | disclosed |
| US-20030119880-A1 | Tetrahydropyridine derivatives acting on muscarinic acetylcholine receptors | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2003-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119880-A1 | Tetrahydropyridine derivatives acting on muscarinic acetylcholine receptors | CHRM1, CHRM3, CHRM2 | LMNA 4729/4885HTT 3679/4885SMN1; SMN2 1483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.