Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 5/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.54 |
| ▸ | P2RY12 | Q9H244 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6767362 | 0.85 | PDE3B (0.65) | PDE3BPDE3AP2RY12GAAPKM | |
| SCHEMBL6768474 | 0.84 | GAA (0.51) | PDE3BPDE3AP2RY12GAAPKM | |
| SCHEMBL6763763 | 0.84 | GAA (0.54) | PDE3BPDE3AP2RY12GAAPKM | |
| SCHEMBL6772923 | 0.82 | GAA (0.49) | PDE3BPDE3AP2RY12GAAPKM | |
| SCHEMBL31239037 | 0.81 | GAA (0.54) | PDE3BPDE3AP2RY12GAAPKM | |
| SCHEMBL6766390 | 0.80 | GAA (0.57) | PDE3BPDE3AP2RY12GAAPKM | |
| SCHEMBL6767765 | 0.79 | KMT2A (0.49) | GAAPKMMAPTALDH1A1KDM4E | |
| SCHEMBL6893722 | 0.79 | GAA (0.49) | PDE3BPDE3AP2RY12GAAPKM | |
| SCHEMBL13303940 | 0.78 | GAA (0.68) | PDE3BPDE3AGAAPKMMAPT | |
| SCHEMBL5373119 | 0.78 | MAPT (0.46) | PDE3BPDE3AP2RY12GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699880-B1 | STIMULATE MUSCARINIC ACETYLCHOLINE RECEPTORS M4, ANALGESICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| EP-1221443-A1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-07-10 | — | — | EP | disclosed |