Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21022829 | 0.87 | NPSR1 (0.46) | KMT2AKDM4EGAAPKMUSP2 | |
| SCHEMBL6763547 | 0.85 | TSHR (0.56) | KMT2AKDM4EGAAPKMALDH1A1 | |
| SCHEMBL20718810 | 0.84 | KDM4E (0.53) | KMT2AKDM4EGAAPKMUSP2 | |
| SCHEMBL20718793 | 0.81 | KDM4E (0.48) | KMT2AKDM4EGAAPKMUSP2 | |
| SCHEMBL6767607 | 0.79 | PDE3B (0.54) | KMT2AKDM4EGAAPKMALDH1A1 | |
| SCHEMBL13306888 | 0.79 | CA1 (0.44) | KMT2AKDM4EGAAPKMALDH1A1 | |
| SCHEMBL9127807 | 0.78 | GLA (0.62) | KMT2AKDM4EGAAALDH1A1GLA | |
| SCHEMBL6766474 | 0.76 | GAA (0.45) | KMT2AKDM4EGAAPKMALDH1A1 | |
| SCHEMBL6768474 | 0.76 | GAA (0.51) | KMT2AKDM4EGAAPKMALDH1A1 | |
| SCHEMBL13303940 | 0.76 | GAA (0.68) | KMT2AKDM4EGAAPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699880-B1 | STIMULATE MUSCARINIC ACETYLCHOLINE RECEPTORS M4, ANALGESICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| EP-1221443-A1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-07-10 | — | — | EP | disclosed |