Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 15/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | CALML3 | P27482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6427947 | 0.83 | F10 (0.31) | GRM2F10CALML3 | |
| SCHEMBL6335767 | 0.82 | MAOA (0.50) | F10CALML3 | |
| SCHEMBL6335763 | 0.82 | MAOA (0.50) | F10CALML3 | |
| SCHEMBL6348267 | 0.82 | MAOA (0.50) | F10CALML3 | |
| SCHEMBL6423688 | 0.81 | MAOA (0.37) | GRM2F10CALML3 | |
| SCHEMBL6337001 | 0.80 | MAOA (0.43) | F10CALML3 | |
| SCHEMBL5460856 | 0.78 | KCNH2 (0.53) | — | |
| SCHEMBL6502558 | 0.75 | F10 (0.35) | F10CALML3 | |
| SCHEMBL8024076 | 0.75 | GRM2 (0.43) | GRM2F10 | |
| SCHEMBL6760962 | 0.74 | GRM2 (0.36) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385834-A1 | BICYCLO[3,1,0]HEXANE CONTAINING OXAZOLIDINONE ANTIBIOTIC AND DERIVATIVES THEREOF | Merck & Co., Inc. (US) | 2004-02-04 | — | — | EP | disclosed |
| WO-2003027083-A1 | BICYCLO[3,1,0]HEXANE CONTAINING OXAZOLIDINONE ANTIBIOTIC AND DERIVATIVES THEREOF | MERCK & CO., INC. (US) | 2003-04-03 | — | — | WO | disclosed |