SCHEMBL8024076

SCHEMBL8024076

NC(=O)CCC1CN(c2ccc(C3=CCOCC3)cc2)C(=O)O1

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 14/20 0.43
F10 P00742 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6398883 0.85 MAOA (0.48) GRM2F10
SCHEMBL6398888 0.85 MAOA (0.48) GRM2F10
SCHEMBL8024116 0.85 MAOA (0.51)
SCHEMBL7153924 0.83 GRM2 (0.42) GRM2F10
SCHEMBL8013254 0.83 GRM2 (0.42) GRM2F10
SCHEMBL6396624 0.81 MAOA (0.56) F10
SCHEMBL6396630 0.81 MAOA (0.56) F10
SCHEMBL9823484 0.79 GRM2 (0.50) GRM2F10
SCHEMBL3567689 0.78 GRM2 (0.47) GRM2F10
SCHEMBL3567695 0.78 GRM2 (0.47) GRM2F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6166056-A Phenyloxazolidinones having a C-C bond to 4-8 membered heterocyclic rings PHARMACIA (US) 2000-12-26 US disclosed