Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6768232 | 0.86 | GAA (0.47) | GAAPKMGRIN2DGRIN3BGRIN1 | |
| SCHEMBL28619121 | 0.81 | GAA (0.53) | GAAPKMGRIN2DGRIN3BGRIN1 | |
| SCHEMBL6772923 | 0.78 | GAA (0.49) | GAAPKMGRIN2DGRIN3BGRIN1 | |
| SCHEMBL6768119 | 0.77 | GAA (0.54) | GAAPKMGRIN2DGRIN3BGRIN1 | |
| SCHEMBL6767765 | 0.76 | KMT2A (0.49) | GAAPKMKDM4EMAPTALDH1A1 | |
| SCHEMBL6767607 | 0.75 | PDE3B (0.54) | GAAPKMGRIN2DGRIN3BGRIN1 | |
| SCHEMBL6766396 | 0.75 | GAA (0.51) | GAAPKMGRIN2DGRIN3BGRIN1 | |
| SCHEMBL6763502 | 0.75 | MEN1 (0.56) | GAAPKMGRIN2DGRIN3BGRIN1 | |
| SCHEMBL13303940 | 0.75 | GAA (0.68) | GAAPKMGRIN2DGRIN3BGRIN1 | |
| SCHEMBL6763763 | 0.74 | GAA (0.54) | GAAPKMGRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699880-B1 | STIMULATE MUSCARINIC ACETYLCHOLINE RECEPTORS M4, ANALGESICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| EP-1221443-A1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-07-10 | — | — | EP | disclosed |