Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 16/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | CALML3 | P27482 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5834227 | 0.88 | MAOA (0.39) | MAOAMAOBCALML3 | |
| SCHEMBL6765838 | 0.84 | MAOA (0.39) | MAOAMAOBCALML3 | |
| SCHEMBL5834614 | 0.82 | MAOA (0.37) | MAOAMAOBCALML3 | |
| SCHEMBL7084688 | 0.82 | MAOA (0.41) | MAOAMAOBCALML3 | |
| SCHEMBL7080989 | 0.82 | MAOA (0.41) | MAOAMAOBCALML3 | |
| SCHEMBL5833669 | 0.82 | MAOA (0.40) | MAOAMAOBCALML3 | |
| SCHEMBL7077019 | 0.81 | CALML3 (0.49) | MAOAMAOBCALML3 | |
| SCHEMBL5844285 | 0.81 | MAOA (0.39) | MAOACALML3 | |
| SCHEMBL5833531 | 0.81 | F10 (0.41) | MAOAMAOBCALML3 | |
| SCHEMBL7849558 | 0.78 | MAOB (0.41) | MAOAMAOBCALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6734200-B1 | ANTIBIOTIC COMPOUNDS CONTAINING A SUBSTITUTED OXAZOLIDINONE RING; ACTIVITY AGAINST GRAM-POSITIVE PATHOGENS | ASTRAZENECA AB (SE) | 2004-05-11 | — | — | US | disclosed |
| US-20030207899-A1 | Heterocyclylaminomethyloxazo-lidinones as antibacterials | ASTRAZENECA AB (SE) | 2003-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207899-A1 | Heterocyclylaminomethyloxazo-lidinones as antibacterials | HDHD5, CYP8B1, LSS | MAOA 652/4885MAOB 705/4885CALML3 4410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.