Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28317112 | 0.86 | LMNA (0.58) | GRM2LMNAALDH1A1KDM4ENPSR1 | |
| SCHEMBL30064613 | 0.81 | ALDH1A1 (0.65) | LMNAALDH1A1KDM4ENPSR1MAPT | |
| SCHEMBL14409758 | 0.81 | ALDH1A1 (0.65) | LMNAALDH1A1KDM4ENPSR1MAPT | |
| SCHEMBL28883096 | 0.80 | LMNA (0.60) | GRM2LMNAALDH1A1KDM4ENPSR1 | |
| SCHEMBL6766208 | 0.74 | LMNA (0.56) | GRM2LMNAALDH1A1KDM4ENPSR1 | |
| SCHEMBL16168947 | 0.73 | GRM2 (0.80) | GRM2KMT2A | |
| SCHEMBL28175731 | 0.73 | ALDH1A1 (0.71) | GRM2LMNAALDH1A1KDM4ENPSR1 | |
| SCHEMBL17206631 | 0.72 | KDM4E (0.43) | LMNAALDH1A1KDM4ENPSR1MAPT | |
| SCHEMBL28317085 | 0.71 | CYP1A2 (0.56) | ALDH1A1KDM4ENPSR1MAPTMEN1 | |
| SCHEMBL14850863 | 0.71 | ALDH1A1 (0.56) | GRM2ALDH1A1CYP2A6CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6730418-B2 | HAVING SUPERIOR STABILITY AND LIGHT EMITTING LUMINANCE CHARACTERISTIC AND HAVING LIGHT EMITTING FUNCTION IN YELLOW RED RANGE | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2004-05-04 | — | — | US | disclosed |
| US-20030012980-A1 | Quinoline derivatives and organic electroluminescent devices | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2003-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030012980-A1 | Quinoline derivatives and organic electroluminescent devices | KCNQ1, KCNQ2, RECQL | GRM2 2662/4885LMNA 3072/4885ALDH1A1 567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.