SCHEMBL676830

SCHEMBL676830

C=C1Cc2ccccc2C1=O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.67
CES1 P23141 2/20 0.61
BCHE P06276 1/20 0.61
METAP1 P53582 6/20 0.55
ALDH1A1 P00352 3/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2C19 P33261 1/20 0.52
MIF P14174 4/20 0.48
MAOB P27338 1/20 0.48
KDM4E B2RXH2 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
TDP2 O95551 1/20 0.45
CASP3 P42574 1/20 0.45
CASP7 P55210 1/20 0.45
CASP9 P55211 1/20 0.45
CASP6 P55212 1/20 0.45
CASP8 Q14790 1/20 0.45
MAP3K14 Q99558 1/20 0.45
ACHE P22303 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29073279 0.90 MAOA (0.55) MAOACES1BCHEMETAP1ALDH1A1
Anthrone SCHEMBL29448801 0.80 MAOA (1.00) MAOACES1BCHEALDH1A1CYP1A2
SCHEMBL21538713 0.80
Anthrone SCHEMBL1527782 0.80 MAOA (1.00) MAOACES1BCHEALDH1A1CYP1A2
Anthrone SCHEMBL29357010 0.80 MAOA (1.00) MAOACES1BCHEALDH1A1CYP1A2
SCHEMBL2319027 0.80 MAOA (0.90) MAOACES1BCHEALDH1A1CYP1A2
Anthrone SCHEMBL18143 0.80 MAOA (1.00) MAOACES1BCHEALDH1A1CYP1A2
SCHEMBL1739155 0.80 CES1 (0.71) MAOACES1BCHEALDH1A1MIF
SCHEMBL30303760 0.80 CES1 (0.71) MAOACES1BCHEALDH1A1MIF
Anthrone SCHEMBL22574797 0.78 MAOA (0.95) MAOACES1BCHEALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112961086-B 2-methylene-1-indanone derivative and synthesis method thereof 齐鲁工业大学 2022-10-21 CN claimed
CN-112961086-A 2-methylene-1-indanone derivative and synthesis method thereof 齐鲁工业大学 2021-06-15 CN claimed
JP-4717803-B2 2011-07-06 JP claimed
US-7724330-B2 Biaxial film having local birefringence that varies periodically MERCK PATENT GMBH (DE) 2010-05-25 US claimed
US-7435357-B2 Polymerised liquid crystal film with retardation or orientation pattern MERCK PATENT GMBH (DE) 2008-10-14 US claimed
EP-1763689-B1 BIAXIAL FILM HAVING LOCAL BIREFRINGENCE THAT VARIES PERIODICALLY MERCK PATENT GMBH (DE) 2007-10-31 EP claimed
US-20060193998-A1 Polymerised liquid crystal film with retardation or orientation pattern MERCK PATENT GMBH (DE) 2006-08-31 US claimed
EP-1611189-A1 POLYMERISED LIQUID CRYSTAL FILM WITH RETARDATION OR ORIENTATION PATTERN MERCK PATENT GmbH (DE) 2006-01-04 EP claimed
WO-2004090025-A1 POLYMERISED LIQUID CRYSTAL FILM WITH RETARDATION OR ORIENTATION PATTERN MERCK PATENT GMBH (DE) 2004-10-21 WO claimed
US-6130228-A Polycyclic compounds UNIVERSITY OF STRATHCLYDE (GB) 2000-10-10 US claimed
CN-117659054-B Multi-arm organic photoelectric small molecule and preparation method and application thereof 电子科技大学 2024-03-29 CN disclosed
CN-117659054-B Multi-arm organic photoelectric small molecule and preparation method and application thereof 电子科技大学 2024-03-29 CN disclosed
CN-115377290-B Broad spectrum organic photoelectric detector with short wave infrared response 电子科技大学 2024-03-26 CN disclosed
CN-117659054-A Multi-arm organic photoelectric small molecule and preparation method and application thereof 电子科技大学 2024-03-08 CN disclosed
CN-117659054-A Multi-arm organic photoelectric small molecule and preparation method and application thereof 电子科技大学 2024-03-08 CN disclosed
WO-2004090025-A1 POLYMERISED LIQUID CRYSTAL FILM WITH RETARDATION OR ORIENTATION PATTERN MERCK PATENT GMBH (DE) 2004-10-21 WO disclosed
WO-2003092606-A2 CHOLINESTERASE INHIBITORS TO PREVENT INJURIES CAUSED BY CHEMICALS EISAI CO., LTD. (JP) 2003-11-13 WO disclosed
US-6130228-A Polycyclic compounds UNIVERSITY OF STRATHCLYDE (GB) 2000-10-10 US disclosed
EP-0877735-A1 POLYCYCLIC COMPOUNDS University of Strathclyde (GB) 1998-11-18 EP disclosed
WO-1997019929-A1 POLYCYCLIC COMPOUNDS THE UNIVERSITY OF STRATHCLYDE (GB) 1997-06-05 WO disclosed