Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6774196 | 0.85 | RAB9A (0.48) | NOTUMMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL6769135 | 0.84 | NOTUM (0.58) | NOTUMPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28927301 | 0.80 | NOTUM (0.76) | NOTUMPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27789238 | 0.80 | NOTUM (0.66) | NOTUMPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14959706 | 0.80 | NOTUM (0.66) | NOTUMPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6027760 | 0.80 | NOTUM (0.66) | NOTUMPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2178860 | 0.80 | NOTUM (0.76) | NOTUMPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL541967 | 0.77 | NOTUM (0.72) | NOTUMPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2412732 | 0.77 | NOTUM (0.71) | NOTUMPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6769057 | 0.77 | CYP2C19 (0.58) | POLBMEN1KMT2ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723724-B2 | PSYCHOLOGICAL DISORDERS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2004-04-20 | — | — | US | disclosed |
| US-20020119983-A1 | Novel isoxazolylalkylpiperazine derivatives having selective biological activity at dopamine D3 or D4 receptor, and preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2002-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020119983-A1 | Novel isoxazolylalkylpiperazine derivatives having selective biological activity at dopamine D3 or D4 receptor, and preparation thereof | DRD4, DRD3, DRD2 | NOTUM 4474/4885POLB 3948/4885MEN1 4813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.