Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6767449 | 0.99 | MAPK14 (0.51) | MAPK14KDM4EHTR2AKCNH2HTR2C | |
| SCHEMBL5780821 | 0.92 | KDM4E (0.48) | MAPK14KDM4EHTR2AKCNH2FLT3 | |
| Hydrochloric Acid SCHEMBL5781450 | 0.91 | KDM4E (0.48) | MAPK14KDM4EHTR2AKCNH2FLT3 | |
| SCHEMBL5780359 | 0.87 | KDM4E (0.49) | MAPK14KDM4EHTR2AKCNH2HTR2C | |
| Hydrochloric Acid SCHEMBL5782752 | 0.86 | KDM4E (0.48) | MAPK14KDM4EHTR2AHTR2CFLT3 | |
| SCHEMBL5777171 | 0.84 | POLB (0.52) | MAPK14KDM4EPOLBL3MBTL1BRD4 | |
| SCHEMBL5779094 | 0.84 | KDM4E (0.54) | KDM4EPOLBL3MBTL1BRD4USP2 | |
| Hydrochloric Acid SCHEMBL5783222 | 0.84 | POLB (0.51) | MAPK14KDM4EPOLBL3MBTL1BRD4 | |
| Hydrochloric Acid SCHEMBL6768032 | 0.83 | KDM4E (0.53) | KDM4EPOLBL3MBTL1BRD4USP2 | |
| Hydrochloric Acid SCHEMBL7822416 | 0.78 | OXTR (0.52) | KDM4EPOLBL3MBTL1USP2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1153922-A1 | HETERODIAZINONE DERIVATIVES | Eisai Co., Ltd. (JP) | 2001-11-14 | — | — | EP | claimed |
| US-6825192-B1 | NON-N-METHYL-D-ASPARTATE (NON- NMDA) EXCITATORY AMINO ACID RECEPTOR ANTAGONISTIC ACTION, FOR EXAMPLE 2-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLE PROPIONIC ACID (AMPA) RECEPTOR ANTAGONISTIC ACTION | EISAI CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| EP-1153922-A1 | HETERODIAZINONE DERIVATIVES | Eisai Co., Ltd. (JP) | 2001-11-14 | — | — | EP | disclosed |