Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD5 | P21918 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5782752 | 0.99 | KDM4E (0.48) | KDM4EMAPK14POLBL3MBTL1USP2 | |
| SCHEMBL5779094 | 0.93 | KDM4E (0.54) | KDM4EPOLBL3MBTL1USP2BRD4 | |
| Hydrochloric Acid SCHEMBL6768032 | 0.92 | KDM4E (0.53) | KDM4EPOLBL3MBTL1USP2BRD4 | |
| SCHEMBL5780821 | 0.88 | KDM4E (0.48) | KDM4EMAPK14POLBL3MBTL1USP2 | |
| SCHEMBL6768404 | 0.87 | MAPK14 (0.51) | KDM4EMAPK14POLBL3MBTL1USP2 | |
| Hydrochloric Acid SCHEMBL5781450 | 0.87 | KDM4E (0.48) | KDM4EMAPK14POLBL3MBTL1USP2 | |
| Hydrochloric Acid SCHEMBL6767449 | 0.86 | MAPK14 (0.51) | KDM4EMAPK14POLBL3MBTL1USP2 | |
| SCHEMBL6763534 | 0.85 | KDM4E (0.50) | KDM4EPOLBL3MBTL1DRD1DRD4 | |
| SCHEMBL6763508 | 0.84 | KDM4E (0.52) | KDM4EPOLBL3MBTL1HTR2CHTR2B | |
| SCHEMBL5777171 | 0.84 | POLB (0.52) | KDM4EMAPK14POLBL3MBTL1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1153922-B1 | HETERODIAZINONE DERIVATIVES | EISAI CO LTD (JP) | 2006-04-26 | — | — | EP | claimed |
| EP-1153922-A1 | HETERODIAZINONE DERIVATIVES | Eisai Co., Ltd. (JP) | 2001-11-14 | — | — | EP | claimed |
| EP-1153922-B1 | HETERODIAZINONE DERIVATIVES | EISAI CO LTD (JP) | 2006-04-26 | — | — | EP | disclosed |
| US-6825192-B1 | NON-N-METHYL-D-ASPARTATE (NON- NMDA) EXCITATORY AMINO ACID RECEPTOR ANTAGONISTIC ACTION, FOR EXAMPLE 2-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLE PROPIONIC ACID (AMPA) RECEPTOR ANTAGONISTIC ACTION | EISAI CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| EP-1153922-A1 | HETERODIAZINONE DERIVATIVES | Eisai Co., Ltd. (JP) | 2001-11-14 | — | — | EP | disclosed |