Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.49 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NOS1 | P29475 | 1/20 | 0.48 |
| ▸ | HMOX2 | P30519 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGAV | P06756 | 2/20 | 0.44 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6771544 | 0.80 | ITGB1 (0.51) | L3MBTL1ITGB1ITGA5KDM4EALDH1A1 | |
| SCHEMBL7029988 | 0.78 | ITGB1 (0.55) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL10861718 | 0.77 | CYP1A2 (0.66) | KDM4EALDH1A1ITGB3ITGAVCYP1A2 | |
| SCHEMBL6771600 | 0.76 | ITGB1 (0.44) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL10858528 | 0.75 | CYP1A2 (0.63) | KDM4EALDH1A1ITGB3ITGAVCYP1A2 | |
| SCHEMBL2801030 | 0.75 | MAOB (0.60) | HTTRAB9AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL9644591 | 0.75 | CYP1A2 (0.63) | KDM4EALDH1A1ITGB3ITGAVCYP1A2 | |
| SCHEMBL6472975 | 0.74 | CYP1A2 (0.55) | RAB9AKDM4EALDH1A1CYP1A2MAPT | |
| SCHEMBL6771776 | 0.74 | ITGB1 (0.55) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL7162438 | 0.74 | MAOB (0.62) | HTTRAB9AL3MBTL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6833366-B1 | Dihydrostilbene alkanoic acid derivatives | PHARMACIA CORPORATION | 2004-12-21 | — | — | US | disclosed |
| US-6720315-B2 | FOR INHIBITING BONE RESORPTION, PERIODONTAL DISEASE, OSTEOPOROSIS, HUMORAL HYPERCALCEMIA OF MALIGNANCY, PAGET'S DISEASE, TUMOR METASTASIS, SOLID TUMOR GROWTH, ANGIOGENESIS, MACULAR DEGENERATION AND DIABETIC RETINOPATHY RETINOPATHY | PHARMACIA CORPORATION | 2004-04-13 | — | — | US | disclosed |
| EP-1289959-A1 | DIHYDROSTILBENE ALKANOIC ACID DERIVATIVES USEFUL AS VITRONECTIN ANTAGONISTS | Pharmacia Corporation (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096310-A1 | DIHYDROSTILBENE ALKANOIC ACID DERIVATIVES USEFUL AS VITRONECTIN ANTAGONISTS | PHARMACIA CORPORATION (US) | 2001-12-20 | — | — | WO | disclosed |