Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 8/20 | 0.51 |
| ▸ | ITGA5 | P08648 | 4/20 | 0.51 |
| ▸ | F2 | P00734 | 3/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 12/20 | 0.46 |
| ▸ | ITGAV | P06756 | 12/20 | 0.46 |
| ▸ | ITGB5 | P18084 | 4/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.46 |
| ▸ | ITGB6 | P18564 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6774349 | 0.84 | ITGB3 (0.51) | ITGB1ITGA5F2ITGB3ITGAV | |
| SCHEMBL6772284 | 0.81 | RAB9A (0.55) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL6768513 | 0.81 | ITGB3 (0.56) | ITGB1ITGA5F2ITGB3ITGAV | |
| SCHEMBL6768600 | 0.80 | HTT (0.50) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL6773136 | 0.79 | ITGB3 (0.52) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL6773294 | 0.79 | ITGB3 (0.52) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL7029988 | 0.79 | ITGB1 (0.55) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL6799057 | 0.79 | AKR1C3 (0.52) | ITGB1ITGA5KDM4EALDH1A1LMNA | |
| SCHEMBL6768527 | 0.79 | ITGB3 (0.52) | ITGB1ITGA5F2ITGB3ITGAV | |
| SCHEMBL6771727 | 0.79 | ITGB1 (0.48) | ITGB1ITGA5F2ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6833366-B1 | Dihydrostilbene alkanoic acid derivatives | PHARMACIA CORPORATION | 2004-12-21 | — | — | US | disclosed |
| US-6720315-B2 | FOR INHIBITING BONE RESORPTION, PERIODONTAL DISEASE, OSTEOPOROSIS, HUMORAL HYPERCALCEMIA OF MALIGNANCY, PAGET'S DISEASE, TUMOR METASTASIS, SOLID TUMOR GROWTH, ANGIOGENESIS, MACULAR DEGENERATION AND DIABETIC RETINOPATHY RETINOPATHY | PHARMACIA CORPORATION | 2004-04-13 | — | — | US | disclosed |
| EP-1289959-A1 | DIHYDROSTILBENE ALKANOIC ACID DERIVATIVES USEFUL AS VITRONECTIN ANTAGONISTS | Pharmacia Corporation (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096310-A1 | DIHYDROSTILBENE ALKANOIC ACID DERIVATIVES USEFUL AS VITRONECTIN ANTAGONISTS | PHARMACIA CORPORATION (US) | 2001-12-20 | — | — | WO | disclosed |