Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10362611 | 0.87 | GAA (0.78) | GAAKDM4EALDH1A1KMT2ANPC1 | |
| SCHEMBL10362641 | 0.84 | GAA (0.74) | GAAKDM4EALDH1A1KMT2ANPC1 | |
| SCHEMBL10364418 | 0.84 | GAA (0.69) | GAAKDM4EALDH1A1KMT2ANPC1 | |
| SCHEMBL8458301 | 0.83 | CFD (0.65) | GAAKDM4EALDH1A1KMT2ANPC1 | |
| SCHEMBL10363515 | 0.83 | GAA (1.00) | GAAKDM4EALDH1A1KMT2ANPC1 | |
| SCHEMBL10362772 | 0.83 | ALDH1A1 (0.75) | GAAKDM4EALDH1A1KMT2ANPC1 | |
| SCHEMBL10362736 | 0.82 | GAA (0.70) | GAAKDM4EALDH1A1KMT2ANPC1 | |
| SCHEMBL10363617 | 0.82 | GAA (0.70) | GAAKDM4EALDH1A1KMT2ANPC1 | |
| SCHEMBL29098671 | 0.82 | GAA (0.70) | GAAKDM4EALDH1A1KMT2ANPC1 | |
| SCHEMBL1589861 | 0.81 | KMT2A (0.78) | GAAKDM4EALDH1A1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686353-B1 | PREVENTING BLOOD MONOCYTES AND LYMPHOCYTES FROM INFILTRATING TISSUE | TEIJIN INTELLECTUAL PROPERTY CENTER LIMITED (JP) | 2004-02-03 | — | — | US | disclosed |
| EP-0914319-B1 | DIARYLALKYL CYCLIC DIAMINE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS | TEIJIN LTD (JP) | 2001-11-21 | — | — | EP | disclosed |