Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6775234 | 0.92 | TLR7 (0.44) | TLR7TLR8NPC1RAB9AHDAC3 | |
| SCHEMBL6775141 | 0.91 | TLR7 (0.51) | TLR7TLR8TP53DRD4DRD3 | |
| SCHEMBL6778794 | 0.91 | SMN1; SMN2 (0.48) | TLR7TLR8NPC1RAB9ADRD4 | |
| SCHEMBL6768551 | 0.89 | TLR7 (0.42) | TLR7TLR8NPC1RAB9AHDAC3 | |
| SCHEMBL6772194 | 0.89 | TLR7 (0.42) | TLR7TLR8NPC1RAB9ADRD3 | |
| SCHEMBL6774230 | 0.88 | TLR7 (0.44) | TLR7TLR8TP53NPC1RAB9A | |
| SCHEMBL6779049 | 0.87 | DRD2 (0.45) | TLR7TLR8TP53DRD4DRD3 | |
| SCHEMBL6773865 | 0.85 | SMN1; SMN2 (0.52) | TLR7TLR8TP53NPC1RAB9A | |
| SCHEMBL6772917 | 0.85 | TLR7 (0.45) | TLR7TLR8DRD3DRD2ADRA1A | |
| SCHEMBL6768616 | 0.84 | MCHR1 (0.47) | TLR7TLR8TP53NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |