Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 10/20 | 0.46 |
| ▸ | DRD2 | P14416 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6778794 | 0.90 | SMN1; SMN2 (0.48) | MAPTDRD4MEN1KMT2ATLR8 | |
| SCHEMBL6775141 | 0.89 | TLR7 (0.51) | MAPTDRD4DRD2TLR8TLR7 | |
| SCHEMBL6779968 | 0.89 | MCHR1 (0.47) | MCHR1GAATLR8TLR7NAMPT | |
| SCHEMBL6779049 | 0.89 | DRD2 (0.45) | DRD4DRD2MEN1KMT2ATLR8 | |
| SCHEMBL6772917 | 0.88 | TLR7 (0.45) | DRD2TLR8TLR7DRD3NAMPT | |
| SCHEMBL6776505 | 0.88 | PKM (0.45) | MCHR1MAPTKMT2ANPC1HTT | |
| SCHEMBL6773863 | 0.85 | GAA (0.47) | MCHR1GAAMAPTDRD4DRD2 | |
| SCHEMBL6771963 | 0.85 | MAPT (0.46) | MCHR1GAAMAPTDRD4DRD2 | |
| SCHEMBL6768640 | 0.84 | TLR7 (0.43) | GAAMAPTDRD4DRD2MEN1 | |
| SCHEMBL6772194 | 0.84 | TLR7 (0.42) | TLR8TLR7NPC1RAB9ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |