Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 5/20 | 0.55 |
| ▸ | CES2 | O00748 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | DAO | P14920 | 1/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiobenzoic Acid SCHEMBL26983522 | 0.94 | CES1 (0.55) | CES1CES2TSHRALDH1A1DAO | |
| Thiobenzoic Acid SCHEMBL2165570 | 0.94 | CES1 (0.55) | CES1CES2TSHRALDH1A1DAO | |
| Thiobenzoic Acid SCHEMBL11322369 | 0.94 | CES1 (0.55) | CES1CES2TSHRALDH1A1DAO | |
| Thiobenzoic Acid SCHEMBL10405316 | 0.94 | CES1 (0.55) | CES1CES2TSHRALDH1A1DAO | |
| Thiobenzoic Acid SCHEMBL6890936 | 0.94 | CES1 (0.55) | CES1CES2TSHRALDH1A1DAO | |
| Thiobenzoic Acid SCHEMBL284147 | 0.94 | CES1 (0.55) | CES1CES2TSHRALDH1A1DAO | |
| Thiobenzoic Acid SCHEMBL7898028 | 0.94 | CES1 (0.55) | CES1CES2TSHRALDH1A1DAO | |
| Thiobenzoic Acid SCHEMBL22721210 | 0.94 | CES1 (0.55) | CES1CES2TSHRALDH1A1DAO | |
| Thiobenzoic Acid SCHEMBL20741483 | 0.94 | CES1 (0.55) | CES1CES2TSHRALDH1A1DAO | |
| Thiobenzoic Acid SCHEMBL3343877 | 0.94 | CES1 (0.55) | CES1CES2TSHRALDH1A1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723717-B1 | CARDIAC-SPARING; SIDE EFFECT REDUCTION | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 2004-04-20 | — | — | US | disclosed |
| EP-1194405-A1 | SULFUR-CONTAINING THYROXANE DERIVATIVES AND THEIR USE AS HAIR GROWTH PROMOTORS | UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER (US) | 2002-04-10 | — | — | EP | disclosed |
| WO-2000073265-A1 | SULFUR-CONTAINING THYROXANE DERIVATIVES AND THEIR USE AS HAIR GROWTH PROMOTORS | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTRE (US) | 2000-12-07 | — | — | WO | disclosed |