Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Thiobenzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 5/20 | 0.55 |
| ▸ | CES2 | O00748 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | DAO | P14920 | 1/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiobenzoic Acid SCHEMBL26983522 | 0.94 | CES1 (0.55) | CES1CES2TSHRALDH1A1DAO | |
| Thiobenzoic Acid SCHEMBL2165570 | 0.94 | CES1 (0.55) | CES1CES2TSHRALDH1A1DAO | |
| Thiobenzoic Acid SCHEMBL11322369 | 0.94 | CES1 (0.55) | CES1CES2TSHRALDH1A1DAO | |
| Thiobenzoic Acid SCHEMBL6768672 | 0.94 | CES1 (0.55) | CES1CES2TSHRALDH1A1DAO | |
| Thiobenzoic Acid SCHEMBL10405316 | 0.94 | CES1 (0.55) | CES1CES2TSHRALDH1A1DAO | |
| Thiobenzoic Acid SCHEMBL284147 | 0.94 | CES1 (0.55) | CES1CES2TSHRALDH1A1DAO | |
| Thiobenzoic Acid SCHEMBL7898028 | 0.94 | CES1 (0.55) | CES1CES2TSHRALDH1A1DAO | |
| Thiobenzoic Acid SCHEMBL20741483 | 0.94 | CES1 (0.55) | CES1CES2TSHRALDH1A1DAO | |
| Thiobenzoic Acid SCHEMBL22721210 | 0.94 | CES1 (0.55) | CES1CES2TSHRALDH1A1DAO | |
| Thiobenzoic Acid SCHEMBL3343877 | 0.94 | CES1 (0.55) | CES1CES2TSHRALDH1A1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020148347-A1 | AG2S NANOPARTICLES AND METHODS OF PRODUCTION THEREOF | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 2020-07-23 | — | — | WO | claimed |
| US-10421901-B2 | Preparation method of near-infrared silver sulfide quantum dots | Suzhou Institute of Nano-tech and Nano-bionics, Chinese Academy of Sciences (CN) | 2019-09-24 | — | — | US | claimed |
| EP-2716733-B1 | PREPARATION METHOD FOR NEAR-INFRARED SILVER SULFIDE QUANTUM DOTS | SUZHOU INST NANO TECH & NANO B (CN) | 2016-10-26 | — | — | EP | claimed |
| US-20160083647-A1 | Preparation Method of Near-Infrared Silver Sulfide Quantum Dots | Suzhou Institute of Nano-tech and Nano-bionics, Chinese Academy of Sciences (CN) | 2016-03-24 | — | — | US | claimed |
| US-20140087409-A1 | NEAR-INFRARED SILVER SULFIDE QUANTUM DOT, PREPARATION METHOD THEREFOR AND BIOLOGICAL APPLICATION THEREOF | Suzhou Institute of Nano-Bionics, Shinese Academy of Sciences (CN) | 2014-03-27 | — | — | US | claimed |
| US-20210161894-A1 | Compositions and Methods for Modulating Liver Endothelial Cell Fenestrations | LE COUTEUR DAVID (AU) | 2021-06-03 | — | — | US | disclosed |
| CN-112292153-A | Compositions and methods for modulating hepatic endothelial cell fenestration | D·勒库特 | 2021-01-29 | — | — | CN | disclosed |
| EP-3720506-A1 | COMPOSITIONS AND METHODS FOR MODULATING LIVER ENDOTHELIAL CELL FENESTRATIONS | Lecouteur, David (AU) | 2020-10-14 | — | — | EP | disclosed |
| WO-2020148347-A1 | AG2S NANOPARTICLES AND METHODS OF PRODUCTION THEREOF | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 2020-07-23 | — | — | WO | disclosed |
| US-10421901-B2 | Preparation method of near-infrared silver sulfide quantum dots | Suzhou Institute of Nano-tech and Nano-bionics, Chinese Academy of Sciences (CN) | 2019-09-24 | — | — | US | disclosed |
| WO-2019109124-A1 | COMPOSITIONS AND METHODS FOR MODULATING LIVER ENDOTHELIAL CELL FENESTRATIONS | LECOUTEUR DAVID (AU) | 2019-06-13 | — | — | WO | disclosed |
| EP-2716733-B1 | PREPARATION METHOD FOR NEAR-INFRARED SILVER SULFIDE QUANTUM DOTS | SUZHOU INST NANO TECH & NANO B (CN) | 2016-10-26 | — | — | EP | disclosed |
| US-20140087409-A1 | NEAR-INFRARED SILVER SULFIDE QUANTUM DOT, PREPARATION METHOD THEREFOR AND BIOLOGICAL APPLICATION THEREOF | Suzhou Institute of Nano-Bionics, Shinese Academy of Sciences (CN) | 2014-03-27 | — | — | US | disclosed |
| WO-2004108598-A1 | A METHOD OF PREPARING METAL CHALCOGENIDE PARTICLES | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2004-12-16 | — | — | WO | disclosed |
| US-4281052-A | ELECTROSTATIC PRINTING; ADSORPTION OF BY-PRODUCTS BY POROUS PARTICLES SUCH AS AN INORGANIC PIGMENT OR ION EXCHANGER | CANON KABUSHIKI KAISHA (JP) | 1981-07-28 | — | — | US | disclosed |
| US-4273845-A | Heat-developable photosensitive material | CANON KABUSHIKI KAISHA (JP) | 1981-06-16 | — | — | US | disclosed |
| US-4273844-A | Heat-developable photosensitive member for forming electrostatic printing masters | CANON KABUSHIKI KAISHA (JP) | 1981-06-16 | — | — | US | disclosed |
| US-4259424-A | INFRARED RAYS-ABSORBING LAYER IN CONTACT WITH LAYER CONTAINING REDUCIBLE SILVER SALT | CANON KABUSHIKI KAISHA (JP) | 1981-03-31 | — | — | US | disclosed |
| US-4237213-A | THERMOGRAPHY; PHOTOSENSITIVE MATERIAL CONTAINING ORGANIC SILVER SALT, HALIDE, AND BINDER | CANON KABUSHIKI KAISHA (JP) | 1980-12-02 | — | — | US | disclosed |
| US-4106409-A | Electrostatic printing method | CANON KABUSHIKI KAISHA (JP) | 1978-08-15 | — | — | US | disclosed |