Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2919950 | 0.81 | — | — | |
| SCHEMBL5648778 | 0.74 | DPP7 (0.33) | CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9435781 | 0.72 | SLC29A1 (0.32) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL2866247 | 0.72 | L3MBTL1 (0.42) | MEN1KMT2AALDH1A1 | |
| SCHEMBL5646792 | 0.71 | L3MBTL1 (0.40) | MEN1KMT2AALDH1A1 | |
| SCHEMBL2815518 | 0.69 | ALDH1A1 (0.36) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL3053925 | 0.69 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL4973355 | 0.68 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL6632132 | 0.68 | ALDH1A1 (0.36) | MEN1KMT2ACYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL477281 | 0.67 | ALDH1A1 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6833370-B1 | Selectively controlling neurotransmitter release; such as n-((3)-1-(6-chloro-3-pyridinyl)pyrrolidinyl)-n-methylamine | ABBOTT LABORATORIES | 2004-12-21 | — | — | US | disclosed |