Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 19/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5638535 | 0.90 | ACHE (0.71) | ACHE | |
| Zanapezil SCHEMBL678642 | 0.82 | ACHE (1.00) | ACHE | |
| Zanapezil SCHEMBL29366424 | 0.82 | ACHE (1.00) | ACHE | |
| SCHEMBL6765861 | 0.82 | ACHE (0.73) | ACHE | |
| SCHEMBL5636671 | 0.81 | ACHE (0.75) | ACHE | |
| SCHEMBL9204959 | 0.81 | ACHE (1.00) | ACHE | |
| Fumaric Acid SCHEMBL5574975 | 0.80 | ACHE (0.62) | ACHE | |
| Fumaric Acid SCHEMBL5574979 | 0.80 | ACHE (0.62) | ACHE | |
| SCHEMBL9209651 | 0.79 | ACHE (1.00) | ACHE | |
| SCHEMBL6262731 | 0.79 | ACHE (0.68) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1157989-A1 | FLUORIDES OF 4-SUBSTITUTED PIPERIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 2001-11-28 | — | — | EP | claimed |
| US-6677330-B1 | ACETYLCHOLINESTERASE INHIBITORS; TREATING ALZHEIMER*S DISEASE, ATTENTION DEFICIT, HYPERACTIVITY AND BRAIN DISORDERS | EISAI CO., LTD. (JP) | 2004-01-13 | — | — | US | disclosed |
| EP-1157989-A1 | FLUORIDES OF 4-SUBSTITUTED PIPERIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 2001-11-28 | — | — | EP | disclosed |