Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6769163 | 0.81 | RAB9A (0.46) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL6774258 | 0.76 | SMN1; SMN2 (0.40) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL6768362 | 0.76 | DRD2 (0.55) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL20501822 | 0.75 | RAB9A (0.56) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL21200200 | 0.74 | KMT2A (0.55) | ALDH1A1MAPTSMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL21200199 | 0.74 | KMT2A (0.55) | ALDH1A1MAPTSMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL6767117 | 0.73 | MAPT (0.43) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL22348262 | 0.72 | NPC1 (0.56) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL27544629 | 0.72 | NPC1 (0.56) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL22348509 | 0.72 | NPC1 (0.52) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723724-B2 | PSYCHOLOGICAL DISORDERS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2004-04-20 | — | — | US | disclosed |
| US-20020119983-A1 | Novel isoxazolylalkylpiperazine derivatives having selective biological activity at dopamine D3 or D4 receptor, and preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2002-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020119983-A1 | Novel isoxazolylalkylpiperazine derivatives having selective biological activity at dopamine D3 or D4 receptor, and preparation thereof | DRD4, DRD3, DRD2 | ALDH1A1 429/4885NPC1 4523/4885RAB9A 1831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.