Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 3/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 6/20 | 0.38 |
| ▸ | F12 | P00748 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7120850 | 0.80 | ROCK1 (0.45) | PLAUPLATF10ALDH1A1CASP1 | |
| SCHEMBL6776349 | 0.79 | ROCK1 (0.46) | PLAUPLATMTNR1AMTNR1BF10 | |
| SCHEMBL6769241 | 0.78 | ROCK1 (0.45) | PLAUPLATMTNR1AMTNR1BROCK1 | |
| SCHEMBL14752092 | 0.76 | HRH3 (0.40) | F10ALDH1A1HSD17B10 | |
| SCHEMBL6982099 | 0.76 | F12 (0.44) | PLAUPLATF10NCF1F12 | |
| SCHEMBL14404768 | 0.75 | TYMS (0.50) | PLAUALDH1A1HSD17B10NCF1F12 | |
| SCHEMBL29045152 | 0.75 | KDM4E (0.61) | ALDH1A1 | |
| SCHEMBL6775981 | 0.74 | KDM4E (0.40) | PLAUPLATMTNR1AMTNR1BF10 | |
| SCHEMBL1834564 | 0.71 | PLAU (0.59) | PLAUF10NCF1F12NOS3 | |
| SCHEMBL28993960 | 0.71 | NPC1 (0.50) | ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825181-B1 | ORALLY ADMINISTRATED TO EXHIBIT A STRONG ANTICOAGULANT EFFECT BY INHIBITING ACTIVATED BLOOD- COAGULATION FACTOR X | AJINOMOTO CO., INC. (JP) | 2004-11-30 | — | — | US | disclosed |