Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 17/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 16/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6776349 | 0.96 | ROCK1 (0.46) | ROCK1MTNR1AMTNR1BPLAUPLAT | |
| Trifluoroacetic Acid SCHEMBL6775232 | 0.78 | RAD52 (0.42) | — | |
| SCHEMBL6769265 | 0.78 | PLAU (0.43) | ROCK1MTNR1AMTNR1BPLAUPLAT | |
| SCHEMBL7120850 | 0.77 | ROCK1 (0.45) | ROCK1PLAUPLAT | |
| Trifluoroacetic Acid SCHEMBL6769129 | 0.76 | F10 (0.53) | — | |
| Trifluoroacetic Acid SCHEMBL6890249 | 0.76 | F10 (0.49) | ROCK1MTNR1AMTNR1B | |
| SCHEMBL6775414 | 0.76 | ROCK1 (0.41) | ROCK1PLAU | |
| SCHEMBL6982099 | 0.76 | F12 (0.44) | ROCK1PLAUPLAT | |
| SCHEMBL20982809 | 0.76 | L3MBTL1 (0.46) | MTNR1AMTNR1B | |
| Trifluoroacetic Acid SCHEMBL6770182 | 0.75 | NPC1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825181-B1 | ORALLY ADMINISTRATED TO EXHIBIT A STRONG ANTICOAGULANT EFFECT BY INHIBITING ACTIVATED BLOOD- COAGULATION FACTOR X | AJINOMOTO CO., INC. (JP) | 2004-11-30 | — | — | US | disclosed |
| EP-1065200-A1 | AMINOISOQUINOLINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2001-01-03 | — | — | EP | disclosed |