Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 7/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | IL2 | P60568 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6770152 | 0.87 | MME (0.55) | FOLH1NAALAD2ACEMMEL3MBTL1 | |
| SCHEMBL9847998 | 0.87 | FOLH1 (0.54) | FOLH1NAALAD2ACESLC7A5MME | |
| SCHEMBL9847993 | 0.87 | FOLH1 (0.54) | FOLH1NAALAD2ACESLC7A5MME | |
| SCHEMBL246178 | 0.84 | FOLH1 (0.58) | FOLH1NAALAD2ACESLC7A5MME | |
| SCHEMBL4101776 | 0.84 | FOLH1 (0.58) | FOLH1NAALAD2ACESLC7A5MME | |
| SCHEMBL3983123 | 0.81 | FOLH1 (0.59) | FOLH1NAALAD2ACESLC7A5MME | |
| SCHEMBL3983134 | 0.81 | FOLH1 (0.59) | FOLH1NAALAD2ACESLC7A5MME | |
| SCHEMBL27973852 | 0.81 | ACE (0.54) | FOLH1NAALAD2ACESLC7A5MME | |
| SCHEMBL12869808 | 0.80 | FOLH1 (0.61) | FOLH1NAALAD2ACESLC7A5MME | |
| SCHEMBL5738141 | 0.80 | FOLH1 (0.61) | FOLH1NAALAD2ACESLC7A5MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6794492-B2 | N-(2,2,2-TRIFLUOROETHYL)GLYCINE DERIVATIVES; CAN BE USED TO PREPARE LIPOPHILIC PROTEINS ADAPTED FOR CROSSING THE BLOOD BRAIN BARRIER | CLEMSON UNIVERSITY | 2004-09-21 | — | — | US | claimed |