SCHEMBL246178

SCHEMBL246178

CC(F)NC(Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.58
MME P08473 8/20 0.53
ACE P12821 8/20 0.53
CPA1 P15085 1/20 0.53
ACE2 Q9BYF1 1/20 0.53
NAALAD2 Q9Y3Q0 1/20 0.51
SLC7A5 Q01650 1/20 0.49
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4101776 1.00 FOLH1 (0.58) FOLH1MMEACECPA1ACE2
SCHEMBL9847998 0.87 FOLH1 (0.54) FOLH1MMEACECPA1ACE2
SCHEMBL9847993 0.87 FOLH1 (0.54) FOLH1MMEACECPA1ACE2
SCHEMBL5738141 0.87 FOLH1 (0.61) FOLH1MMEACECPA1ACE2
SCHEMBL12869808 0.87 FOLH1 (0.61) FOLH1MMEACECPA1ACE2
SCHEMBL22612664 0.85 FOLH1 (0.60) FOLH1MMEACECPA1ACE2
SCHEMBL29444963 0.85 FOLH1 (0.60) FOLH1MMEACECPA1ACE2
SCHEMBL27973852 0.84 ACE (0.54) FOLH1MMEACECPA1ACE2
SCHEMBL6769407 0.84 FOLH1 (0.51) FOLH1MMEACECPA1ACE2
SCHEMBL5869992 0.83 FOLH1 (0.74) FOLH1MMEACECPA1ACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250049409-A1 METHODS OF QUANTIFYING SKELETAL MUSCLE PERFUSION USING PET IMAGING RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL 2025-02-13 US claimed
JP-2012500036-A 2012-01-05 JP claimed
EP-2318970-A2 MODEL ENHANCED IMAGING Koninklijke Philips Electronics N.V. (NL) 2011-05-11 EP claimed
WO-2010018477-A2 MODEL ENHANCED IMAGING KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2010-02-18 WO claimed
US-20260137765-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF INSTITUT CURIE (FR) 2026-05-21 US disclosed
US-12527854-B2 Methods of producing Shiga toxin B-subunit (STxB) monomers and oligomers, and uses thereof INSTITUT CURIE (FR) 2026-01-20 US disclosed
US-20250281535-A1 ANTI-HUMAN CD45RC BINDING DOMAINS AND USES THEREOF ABOLERIS PHARMA (FR) 2025-09-11 US disclosed
EP-4401842-B1 ANTI-HUMAN CD45RC BINDING DOMAINS AND USES THEREOF ABOLERIS PHARMA (FR) 2025-08-27 EP disclosed
US-20250122300-A1 ANTI-HUMAN CD45RC ANTIBODIES AND USES THEREOF INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2025-04-17 US disclosed
US-20250049409-A1 METHODS OF QUANTIFYING SKELETAL MUSCLE PERFUSION USING PET IMAGING RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL 2025-02-13 US disclosed
US-12168694-B2 Anti-human CD45RC antibodies and uses thereof INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2024-12-17 US disclosed
EP-4401842-A1 ANTI-HUMAN CD45RC BINDING DOMAINS AND USES THEREOF Aboleris Pharma (FR) 2024-07-24 EP disclosed
EP-2511006-A2 System, device and method for preparing tracers and transferring materials during radiosynthesis Siemens Medical Solutions USA, Inc. (US) 2012-10-17 EP disclosed
EP-2408374-A2 FUNCTIONAL IMAGING Koninklijke Philips Electronics N.V. (NL) 2012-01-25 EP disclosed
US-20110299747-A1 FUNCTIONAL IMAGING KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2011-12-08 US disclosed
WO-2010106449-A2 FUNCTIONAL IMAGING KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2010-09-23 WO disclosed
US-20070071671-A1 Process for producing radioactive-fluorine-labeled compound NIHON MEDI-PHYSICS CO., LTD. (JP) 2007-03-29 US disclosed
US-20070036258-A1 Process for producing radioactive fluorine compound NIHON MEDI-PHYSICS CO., LTD. (JP) 2007-02-15 US disclosed
WO-2006110950-A1 IN VIVO MODEL FOR PRECLINICAL DRUG DEVELOPMENT PETER MACCALLUM CANCER INSTITUTE (AU) 2006-10-26 WO disclosed
EP-1683776-A1 PROCESS FOR PRODUCING RADIOACTIVE-FLUORINE-LABELED COMPOUND Nihon Medi-Physics Co., Ltd. (JP) 2006-07-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12527854-B2 Methods of producing Shiga toxin B-subunit (STxB) monomers and oligomers, and uses thereof STXBP1, RNGTT, UPF1 FOLH1 3283/4885MME 333/4885ACE 3069/4885
US-20260137765-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF STXBP1, HBB, UPF1 FOLH1 2969/4885MME 206/4885ACE 3166/4885
US-20070071671-A1 Process for producing radioactive-fluorine-labeled compound PFAS, PFKFB3, PFKFB2 FOLH1 2691/4885MME 1863/4885ACE 3657/4885
US-20070036258-A1 Process for producing radioactive fluorine compound AFF1, AFF4, RER1 FOLH1 3303/4885MME 1441/4885ACE 4032/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.