Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 2/20 | 0.49 |
| ▸ | MERTK | Q12866 | 2/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.47 |
| ▸ | PDE4A | P27815 | 16/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 16/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 16/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 16/20 | 0.45 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6780155 | 0.93 | PDE4A (0.46) | AXLMERTKFLT3YTHDC1PDE4A | |
| SCHEMBL6773096 | 0.81 | YTHDC1 (0.71) | AXLMERTKFLT3YTHDC1PDE4A | |
| SCHEMBL6768490 | 0.80 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6768489 | 0.72 | PDE4A (0.55) | YTHDC1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3582728 | 0.72 | PDE4A (0.51) | YTHDC1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3121249 | 0.66 | POLB (0.48) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6769137 | 0.66 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27387501 | 0.65 | YTHDC1 (1.00) | YTHDC1 | |
| SCHEMBL6865485 | 0.65 | YTHDC1 (0.47) | AXLMERTKFLT3YTHDC1PDE4A | |
| SCHEMBL6675074 | 0.65 | PDE4B (0.57) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043324-B1 | PURINE DERIVATIVES AND MEDICINE CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MITSUBISHI CHEM CORP (JP) | 2004-06-16 | — | — | EP | claimed |
| US-6734187-B1 | ANTIASTHMATIC AGENTS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2004-05-11 | — | — | US | claimed |
| EP-1043324-A1 | PURINE DERIVATIVES AND MEDICINE CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-10-11 | — | — | EP | claimed |
| EP-1043324-B1 | PURINE DERIVATIVES AND MEDICINE CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MITSUBISHI CHEM CORP (JP) | 2004-06-16 | — | — | EP | disclosed |
| US-6734187-B1 | ANTIASTHMATIC AGENTS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2004-05-11 | — | — | US | disclosed |
| EP-1043324-A1 | PURINE DERIVATIVES AND MEDICINE CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-10-11 | — | — | EP | disclosed |