Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | CTSG | P08311 | 1/20 | 0.32 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6769745 | 0.90 | F10 (0.42) | F10TLR7CNR2PTPN1 | |
| SCHEMBL6771027 | 0.88 | F10 (0.36) | F10TLR7 | |
| SCHEMBL7812388 | 0.86 | F10 (0.37) | F10TLR7KLKB1 | |
| SCHEMBL6769298 | 0.86 | F10 (0.37) | F10TLR7KLKB1 | |
| Trifluoroacetic Acid SCHEMBL6771855 | 0.80 | F10 (0.39) | F10TLR7PTPN1 | |
| Trifluoroacetic Acid SCHEMBL6775797 | 0.78 | DHFR (0.40) | F10PTPN1 | |
| Trifluoroacetic Acid SCHEMBL6771022 | 0.78 | F10 (0.40) | F10TLR7PTPN1 | |
| Trifluoroacetic Acid SCHEMBL7812384 | 0.77 | F10 (0.40) | F10TLR7KLKB1PTPN1 | |
| Trifluoroacetic Acid SCHEMBL6769296 | 0.77 | F10 (0.40) | F10TLR7KLKB1PTPN1 | |
| Trifluoroacetic Acid SCHEMBL6890249 | 0.76 | F10 (0.49) | F10KLKB1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825181-B1 | ORALLY ADMINISTRATED TO EXHIBIT A STRONG ANTICOAGULANT EFFECT BY INHIBITING ACTIVATED BLOOD- COAGULATION FACTOR X | AJINOMOTO CO., INC. (JP) | 2004-11-30 | — | — | US | disclosed |
| EP-1065200-A1 | AMINOISOQUINOLINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2001-01-03 | — | — | EP | disclosed |