Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 6/20 | 0.40 |
| ▸ | F10 | P00742 | 4/20 | 0.39 |
| ▸ | GART | P22102 | 4/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.36 |
| ▸ | FOLR2 | P14207 | 1/20 | 0.36 |
| ▸ | FOLR1 | P15328 | 1/20 | 0.36 |
| ▸ | SLC19A1 | P41440 | 1/20 | 0.36 |
| ▸ | SLC46A1 | Q96NT5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6769745 | 0.88 | F10 (0.42) | DHFRF10GARTPTPN1FOLR2 | |
| Trifluoroacetic Acid SCHEMBL6771022 | 0.86 | F10 (0.40) | DHFRF10GARTPTPN1FOLR2 | |
| Trifluoroacetic Acid SCHEMBL6771855 | 0.86 | F10 (0.39) | DHFRF10GARTPTPN1FOLR2 | |
| Trifluoroacetic Acid SCHEMBL7812384 | 0.85 | F10 (0.40) | DHFRF10GARTPTPN1FOLR2 | |
| Trifluoroacetic Acid SCHEMBL6769296 | 0.85 | F10 (0.40) | DHFRF10GARTPTPN1FOLR2 | |
| Trifluoroacetic Acid SCHEMBL6770318 | 0.82 | TRPV1 (0.42) | F10AKT1 | |
| SCHEMBL6769748 | 0.78 | F10 (0.39) | F10PTPN1 | |
| SCHEMBL6775969 | 0.76 | F10 (0.38) | F10PTPN1 | |
| SCHEMBL6771027 | 0.75 | F10 (0.36) | F10 | |
| SCHEMBL7812388 | 0.74 | F10 (0.37) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825181-B1 | ORALLY ADMINISTRATED TO EXHIBIT A STRONG ANTICOAGULANT EFFECT BY INHIBITING ACTIVATED BLOOD- COAGULATION FACTOR X | AJINOMOTO CO., INC. (JP) | 2004-11-30 | — | — | US | disclosed |
| EP-1065200-A1 | AMINOISOQUINOLINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2001-01-03 | — | — | EP | disclosed |