Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 14/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6138879 | 0.86 | AVPR1B (0.38) | AVPR1BEPHX2AOC3 | |
| SCHEMBL6138755 | 0.77 | AOC3 (0.42) | AOC3 | |
| SCHEMBL6138355 | 0.74 | HRH3 (0.47) | — | |
| SCHEMBL6777188 | 0.73 | MMP12 (0.57) | — | |
| SCHEMBL6138498 | 0.68 | HDAC1 (0.45) | EPHX2 | |
| SCHEMBL6138887 | 0.68 | HDAC1 (0.45) | EPHX2 | |
| SCHEMBL6138750 | 0.67 | THRB (0.57) | — | |
| Hydrochloric Acid SCHEMBL6138891 | 0.67 | HDAC1 (0.45) | EPHX2 | |
| Hydrochloric Acid SCHEMBL6138898 | 0.67 | HDAC1 (0.45) | EPHX2 | |
| SCHEMBL65840 | 0.67 | SMN1; SMN2 (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6770644-B1 | Hydroxamic acid derivatives, process for the production thereof and drug containing the same as the active ingredient | ONO PHARMACEUTICALS CO., LTD. (JP) | 2004-08-03 | — | — | US | disclosed |