Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.42 |
| ▸ | PTGIR | P43119 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CD38 | P28907 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6528974 | 0.83 | MAPT (0.55) | MAPTPTGIRDHODHGPR3CRHBP | |
| SCHEMBL6768996 | 0.83 | RAB9A (0.45) | MAPTPTGIRDHODHGPR3CYP1A2 | |
| SCHEMBL6775812 | 0.83 | MAPT (0.43) | MAPTPTGIRDHODHGPR3MEN1 | |
| SCHEMBL6527513 | 0.80 | UTS2R (0.45) | MAPTUTS2RPTGIRDHODHGPR3 | |
| SCHEMBL6768403 | 0.79 | HDAC1 (0.50) | MAPTPTGIRDHODHGPR3EGFR | |
| SCHEMBL6526572 | 0.78 | MAPT (0.56) | MAPTDHODHMEN1KMT2AATM | |
| SCHEMBL6526797 | 0.77 | MAPT (0.50) | MAPTPTGIRDHODHGPR3MEN1 | |
| SCHEMBL6527467 | 0.77 | DHODH (0.43) | MAPTPTGIRDHODHGPR3MEN1 | |
| SCHEMBL6530153 | 0.77 | CYP1A2 (0.42) | MAPTPTGIRDHODHGPR3HDAC6 | |
| SCHEMBL6528050 | 0.77 | CYP1A2 (0.45) | MAPTPTGIRDHODHGPR3CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800656-B2 | Tricyclic compounds and method of treating herpes virus | WARNER LAMBERT COMPANY | 2004-10-05 | — | — | US | claimed |