Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | DHFR | P00374 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GPR3 | P46089 | 1/20 | 0.45 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.45 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.45 |
| ▸ | PTGIR | P43119 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18415610 | 0.88 | CRHBP (0.53) | HDAC1EGFRPTPN1PTPN11DHFR | |
| SCHEMBL6529991 | 0.84 | NPC1 (0.55) | EGFRMAPT | |
| SCHEMBL6770347 | 0.84 | TRPV1 (0.54) | HDAC1MAPTPTGIRDHODHPRSS12 | |
| SCHEMBL6769890 | 0.84 | NPC1 (0.49) | HDAC1EGFRPTPN1PTPN11DHFR | |
| SCHEMBL6526964 | 0.84 | INSR (0.52) | HDAC1MAPTPTGIRCYP1A2 | |
| SCHEMBL6526369 | 0.82 | MAPT (0.55) | MAPTIDO1 | |
| SCHEMBL12922865 | 0.80 | HTT (0.50) | HDAC1EGFRPTPN1PTPN11DHFR | |
| SCHEMBL6527944 | 0.79 | MAPT (0.43) | MAPTGPR3PTGIRDHODHCYP1A2 | |
| SCHEMBL6528974 | 0.79 | MAPT (0.55) | MAPTGPR3PTGIRDHODHCYP1A2 | |
| SCHEMBL6775812 | 0.79 | MAPT (0.43) | MAPTGPR3PTGIRDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800656-B2 | Tricyclic compounds and method of treating herpes virus | WARNER LAMBERT COMPANY | 2004-10-05 | — | — | US | claimed |