Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.61 |
| ▸ | BACE1 | P56817 | 5/20 | 0.59 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.57 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 4/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6770302 | 1.00 | APP (0.61) | APPBACE1SLC5A1SLC5A2ABCG2 | |
| SCHEMBL6770519 | 0.91 | CYSLTR2 (0.58) | APPBACE1SLC5A1SLC5A2MAOB | |
| SCHEMBL6770521 | 0.91 | CYSLTR2 (0.58) | APPBACE1SLC5A1SLC5A2MAOB | |
| SCHEMBL6772382 | 0.89 | CTSV (0.50) | APPBACE1MEN1KMT2AMAPT | |
| SCHEMBL6772371 | 0.89 | CTSV (0.50) | APPBACE1MEN1KMT2AMAPT | |
| SCHEMBL6770154 | 0.88 | BACE1 (0.48) | APPBACE1SLC5A1SLC5A2ABCG2 | |
| SCHEMBL6770151 | 0.88 | BACE1 (0.48) | APPBACE1SLC5A1SLC5A2ABCG2 | |
| SCHEMBL6771118 | 0.88 | BACE1 (0.55) | APPBACE1SLC5A1SLC5A2MEN1 | |
| SCHEMBL6771112 | 0.88 | BACE1 (0.55) | APPBACE1SLC5A1SLC5A2MEN1 | |
| SCHEMBL6776282 | 0.87 | BACE1 (0.47) | APPBACE1SLC5A1SLC5A2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6683095-B2 | ANTICARCINOGENIC AGENTS; ANTIPROLIFERATION AGENTS | LG LIFE SCIENCES LTD. (KR) | 2004-01-27 | — | — | US | disclosed |
| US-20030125356-A1 | Cdk inhibitors having 3-hydroxychromen-4-one structure | LG LIFE SCIENCES LTD. (KR) | 2003-07-03 | — | — | US | disclosed |
| EP-1280789-A1 | CDK INHIBITORS HAVING 3-HYDROXYCHROMEN-4-ONE STRUCTURE | LG Life Sciences Ltd. (KR) | 2003-02-05 | — | — | EP | disclosed |
| WO-2001083469-A1 | CDK INHIBITORS HAVING 3-HYDROXYCHROMEN-4-ONE STRUCTURE | LG LIFE SCIENCES LTD. (KR) | 2001-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125356-A1 | Cdk inhibitors having 3-hydroxychromen-4-one structure | CDK4, CDK3, CDK6 | APP 4466/4885BACE1 3740/4885SLC5A1 1621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.