Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.58 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 5/20 | 0.54 |
| ▸ | MAOB | P27338 | 4/20 | 0.54 |
| ▸ | TLR4 | O00206 | 2/20 | 0.54 |
| ▸ | TLR2 | O60603 | 2/20 | 0.54 |
| ▸ | COMT | P21964 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.47 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.47 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6770521 | 1.00 | CYSLTR2 (0.58) | CYSLTR2CYSLTR1ALDH1A1KDM4EPKM | |
| SCHEMBL6770302 | 0.91 | APP (0.61) | KDM4EBACE1MAOBAPPSMN1; SMN2 | |
| SCHEMBL6770296 | 0.91 | APP (0.61) | KDM4EBACE1MAOBAPPSMN1; SMN2 | |
| SCHEMBL6772371 | 0.86 | CTSV (0.50) | ALDH1A1KDM4EBACE1APPLMNA | |
| SCHEMBL6772382 | 0.86 | CTSV (0.50) | ALDH1A1KDM4EBACE1APPLMNA | |
| SCHEMBL6770151 | 0.86 | BACE1 (0.48) | ALDH1A1KDM4EBACE1MAOAMAOB | |
| SCHEMBL6770154 | 0.86 | BACE1 (0.48) | ALDH1A1KDM4EBACE1MAOAMAOB | |
| SCHEMBL6771112 | 0.85 | BACE1 (0.55) | KDM4EBACE1APPSMN1; SMN2SLC5A1 | |
| SCHEMBL6771118 | 0.85 | BACE1 (0.55) | KDM4EBACE1APPSMN1; SMN2SLC5A1 | |
| SCHEMBL6776282 | 0.84 | BACE1 (0.47) | ALDH1A1KDM4EBACE1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6683095-B2 | ANTICARCINOGENIC AGENTS; ANTIPROLIFERATION AGENTS | LG LIFE SCIENCES LTD. (KR) | 2004-01-27 | — | — | US | disclosed |
| US-20030125356-A1 | Cdk inhibitors having 3-hydroxychromen-4-one structure | LG LIFE SCIENCES LTD. (KR) | 2003-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125356-A1 | Cdk inhibitors having 3-hydroxychromen-4-one structure | CDK4, CDK3, CDK6 | CYSLTR2 2752/4885CYSLTR1 1974/4885ALDH1A1 1157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.