Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.60 |
| ▸ | MAOA | P21397 | 4/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.58 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.54 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | KRAS | P01116 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6770393 | 1.00 | MAOB (0.60) | MAOBMAOAHSP90AA1NR2F2ADAM17 | |
| SCHEMBL6771857 | 0.83 | MAPT (0.47) | MAOBMAOAHSP90AA1MAPTGPR35 | |
| SCHEMBL6771863 | 0.83 | MAPT (0.47) | MAOBMAOAHSP90AA1MAPTGPR35 | |
| SCHEMBL6767061 | 0.81 | TUBB1 (0.56) | MAOAHSP90AA1MAPTMEN1KMT2A | |
| SCHEMBL6767057 | 0.81 | TUBB1 (0.56) | MAOAHSP90AA1MAPTMEN1KMT2A | |
| SCHEMBL6770296 | 0.80 | APP (0.61) | MAOBMAPTMEN1KMT2A | |
| SCHEMBL6770302 | 0.80 | APP (0.61) | MAOBMAPTMEN1KMT2A | |
| SCHEMBL13450131 | 0.80 | DBH (0.64) | MAPTKRASALDH1A1LMNAPTGS2 | |
| SCHEMBL31406952 | 0.79 | GPR35 (0.56) | MAOBMAOAMAPTPOLBMEN1 | |
| SCHEMBL31406953 | 0.79 | GPR35 (0.56) | MAOBMAOAMAPTPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6683095-B2 | ANTICARCINOGENIC AGENTS; ANTIPROLIFERATION AGENTS | LG LIFE SCIENCES LTD. (KR) | 2004-01-27 | — | — | US | disclosed |
| US-20030125356-A1 | Cdk inhibitors having 3-hydroxychromen-4-one structure | LG LIFE SCIENCES LTD. (KR) | 2003-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125356-A1 | Cdk inhibitors having 3-hydroxychromen-4-one structure | CDK4, CDK3, CDK6 | MAOB 2802/4885MAOA 2677/4885HSP90AA1 1580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.