SCHEMBL6770416

SCHEMBL6770416

N#Cc1c(C(=O)Cl)nn(-c2ccc(Cl)cc2Cl)c1Cl

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.53
MEN1 O00255 1/20 0.53
MAPT P10636 1/20 0.53
MAPK1 P28482 1/20 0.53
KMT2A Q03164 1/20 0.53
CNR1 P21554 9/20 0.50
ALDH1A1 P00352 1/20 0.47
CNR2 P34972 7/20 0.43
LMNA P02545 1/20 0.43
RPA1 P27694 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6886607 0.90 KDM4E (0.53) KDM4EMEN1MAPTMAPK1KMT2A
Hydrochloric Acid SCHEMBL6770419 0.88 KDM4E (0.52) KDM4EMEN1MAPTMAPK1KMT2A
SCHEMBL6766067 0.82 MAPT (0.74) KDM4EMEN1MAPTMAPK1KMT2A
SCHEMBL3828981 0.75 CNR1 (0.68) CNR1CNR2RPA1
SCHEMBL13955261 0.74 LMNA (0.59) CNR1ALDH1A1CNR2LMNA
SCHEMBL8018662 0.72 CNR1 (0.63) CNR1CNR2
SCHEMBL3827684 0.72 CNR1 (0.70) CNR1CNR2
SCHEMBL13191030 0.72 CNR1 (0.68) KDM4EMEN1MAPTMAPK1KMT2A
SCHEMBL4481055 0.72 CNR1 (0.72) CNR1CNR2
SCHEMBL13664195 0.71 KDM4E (0.50) KDM4EMEN1MAPTMAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040235926-A1 Cannabinoid receptor ligands and uses thereof PFIZER INC. 2004-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040235926-A1 Cannabinoid receptor ligands and uses thereof CNR1, CNR2, GPR18 KDM4E 3327/4885MEN1 4525/4885MAPT 2665/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.