Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.38 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6167949 | 0.88 | ABCG2 (0.44) | ABCG2CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL6770489 | 0.87 | DHODH (0.35) | — | |
| SCHEMBL6772625 | 0.87 | CSNK2A2 (0.34) | ABCG2CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL6770603 | 0.82 | CSNK2A2 (0.40) | ABCG2CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL6767118 | 0.81 | HTT (0.40) | ABCG2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6769517 | 0.81 | SRC (0.39) | ABCG2CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL6771250 | 0.80 | OPRM1 (0.45) | ABCG2CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL6771234 | 0.80 | CSNK2A2 (0.35) | ABCG2CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL6771827 | 0.79 | ABCG2 (0.37) | ABCG2CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL6769536 | 0.79 | OPRM1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716856-B1 | CELL PROLIFERATIVE DISORDERS OR ALZHEIMER'S DISEASE; REDUCED TOXICITY; CDK/CYCLIN KINASE INHIBITORY ACTIVITY | PHARMACIA & TUBJOHN SPA (IT) | 2004-04-06 | — | — | US | disclosed |