Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | RORC | P51449 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6138439 | 0.84 | HRH3 (0.40) | HRH3RORCPPARA | |
| SCHEMBL6138465 | 0.71 | HDAC1 (0.35) | HRH3 | |
| SCHEMBL6817795 | 0.68 | HDAC2 (0.47) | — | |
| SCHEMBL6817789 | 0.68 | HDAC2 (0.47) | — | |
| SCHEMBL6138877 | 0.65 | HRH3 (0.49) | HRH3RORC | |
| SCHEMBL6138871 | 0.65 | HRH3 (0.49) | HRH3RORC | |
| SCHEMBL6812985 | 0.64 | HDAC2 (0.50) | — | |
| SCHEMBL6812978 | 0.64 | HDAC2 (0.50) | — | |
| SCHEMBL6138387 | 0.63 | MMP13 (0.36) | — | |
| SCHEMBL19398654 | 0.62 | HRH3 (0.43) | HRH3RORCALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6770644-B1 | Hydroxamic acid derivatives, process for the production thereof and drug containing the same as the active ingredient | ONO PHARMACEUTICALS CO., LTD. (JP) | 2004-08-03 | — | — | US | disclosed |