⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7338101 | 0.86 | — | — | |
| SCHEMBL2030841 | 0.84 | TAAR1 (0.71) | — | |
| SCHEMBL20135772 | 0.79 | TAAR1 (0.73) | — | |
| SCHEMBL20146704 | 0.79 | TAAR1 (0.73) | — | |
| SCHEMBL677089 | 0.79 | — | — | |
| SCHEMBL8571535 | 0.77 | TAAR1 (0.70) | — | |
| SCHEMBL6734915 | 0.77 | TAAR1 (0.70) | — | |
| SCHEMBL7116263 | 0.77 | TAAR1 (0.70) | — | |
| SCHEMBL244450 | 0.75 | — | — | |
| SCHEMBL72881 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232654-A1 | Novel Compounds and Compositions as Cathepsin Inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2007-10-04 | — | — | US | claimed |
| US-20040147503-A1 | Antiarthritic agents; muscular dystrophy; antiinflammatory agents; antitumor agents; glomerulonephritis | AXYS PHARMACEUTICALS, INC. | 2004-07-29 | — | — | US | claimed |
| CN-101544655-B | Method for preparing thieno[3,2-c]pyridine derivative | SHANGHAI PHARMACEUTICAL GROUP CO LTD | 2012-07-04 | — | — | CN | disclosed |
| US-7879878-B2 | such as {2-[({[7-(cyclohexylamino)-6-fluoro-4-oxo-1-[(3S)-tetrahydrofuran-3-yl]-1,4-dihydroquinolin-3-yl}carbonyl)amino]ethyl}phosphonic acid, used as platelet aggregation inhibitor and purinergic receptor (P2Y12) inhibitors; therapy for circulatory diseases involving thrombosis via platelet aggregation | ASTELLAS PHARMA INC. (JP) | 2011-02-01 | — | — | US | disclosed |
| EP-1335907-B1 | PIPERAZINYLPYRAZINE COMPOUNDS AS AGONIST OR ANTAGONIST OF SEROTONIN 5HT-2 RECEPTOR | BIOVITRUM AB PUBL (SE) | 2010-06-09 | — | — | EP | disclosed |
| US-7700628-B2 | Aromatic ether derivatives useful as thrombin inhibitors | ELI LILLY AND COMPANY (US) | 2010-04-20 | — | — | US | disclosed |
| EP-1817287-B1 | AROMATIC ETHER DERIVATIVES USEFUL AS THROMBIN INHIBITORS | LILLY CO ELI (US) | 2010-02-10 | — | — | EP | disclosed |
| CN-101544655-A | Method for preparing thieno[3,2-c]pyridine derivative | SHANGHAI PHARMACEUTICAL GROUP | 2009-09-30 | — | — | CN | disclosed |
| US-20090227566-A1 | AROMATIC ETHER DERIVATIVES USEFUL AS THROMBIN INHIBITORS | ELI LILLY AND COMPANY | 2009-09-10 | — | — | US | disclosed |
| US-20090124617-A1 | QUINOLONE DERIVATIVE OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2009-05-14 | — | — | US | disclosed |
| US-7488739-B2 | Quinolone derivative or salt thereof | ASTELLAS PHARMA INC. (JP) | 2009-02-10 | — | — | US | disclosed |
| CN-1255924-A | New process for prepn. of pharmacologically active substance | SANOFI SA (FR) | 2000-06-07 | — | — | CN | disclosed |
| WO-2000027840-A1 | PROCESS FOR RACEMIZATION | SANOFI-SYNTHELABO (FR) | 2000-05-18 | — | — | WO | disclosed |
| EP-0981525-A1 | (2-(2-THIENYL)-ETHYLAMINO)-(2-HALOPHENYL)-ACETONITRILES AS INTERMEDIATES AND PROCESS FOR THE PREPARATION THEREOF | SANOFI-SYNTHELABO (FR) | 2000-03-01 | — | — | EP | disclosed |
| WO-1998051682-A1 | NEW INTERMEDIATES AND PROCESS FOR THE PREPARATION THEREOF | SANOFI-SYNTHELABO (FR) | 1998-11-19 | — | — | WO | disclosed |
| EP-0562832-A1 | Indole and indazole derivatives, for the treatment and prophylaxis of cerebral disorders, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1993-09-29 | — | — | EP | disclosed |
| EP-0232623-B1 | 1-CARBACEPHALOSPORIN ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4892942-A | 1-CARBA (DETHIA)CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1990-01-09 | — | — | US | disclosed |
| US-4791106-A | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1988-12-13 | — | — | US | disclosed |
| EP-0232623-A1 | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1987-08-19 | — | — | EP | disclosed |