Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24932409 | 0.79 | KMT2A (0.65) | HPGDSMN1; SMN2ALDH1A1HDAC3NPC1 | |
| SCHEMBL27996731 | 0.78 | SMN1; SMN2 (0.73) | HPGDSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL11715571 | 0.77 | ALDH1A1 (0.74) | HPGDSMN1; SMN2ALDH1A1PKMNPC1 | |
| SCHEMBL12666949 | 0.75 | HPGD (0.63) | HPGDSMN1; SMN2ALDH1A1HDAC3PKM | |
| SCHEMBL14117959 | 0.75 | ALDH1A1 (0.56) | HPGDSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL13484481 | 0.74 | SMN1; SMN2 (0.62) | HPGDSMN1; SMN2ALDH1A1HDAC3PKM | |
| SCHEMBL11551155 | 0.74 | ALDH1A1 (0.58) | HPGDSMN1; SMN2ALDH1A1PKMNPC1 | |
| SCHEMBL15267942 | 0.74 | SMN1; SMN2 (0.62) | HPGDSMN1; SMN2ALDH1A1HDAC3PKM | |
| SCHEMBL21833012 | 0.74 | SMN1; SMN2 (0.62) | HPGDSMN1; SMN2ALDH1A1HDAC3NPC1 | |
| SCHEMBL27405353 | 0.74 | SMN1; SMN2 (0.62) | HPGDSMN1; SMN2ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686353-B1 | PREVENTING BLOOD MONOCYTES AND LYMPHOCYTES FROM INFILTRATING TISSUE | TEIJIN INTELLECTUAL PROPERTY CENTER LIMITED (JP) | 2004-02-03 | — | — | US | disclosed |
| EP-0914319-B1 | DIARYLALKYL CYCLIC DIAMINE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS | TEIJIN LTD (JP) | 2001-11-21 | — | — | EP | disclosed |
| EP-0914319-A1 | DIARYLALKYL CYCLIC DIAMINE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS | TEIJIN LIMITED (JP) | 1999-05-12 | — | — | EP | disclosed |
| WO-1997044329-A9 | DIARYLALKYL CYCLIC DIAMINE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS | — | 1998-03-12 | — | — | WO | disclosed |
| WO-1997044329-A1 | DIARYLALKYL CYCLIC DIAMINE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS | TEIJIN LIMITED (JP) | 1997-11-27 | — | — | WO | disclosed |