SCHEMBL6771389

SCHEMBL6771389

C1=CCOC=C1.c1ccc2c(-c3cccc4ccccc34)cccc2c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 1/20 0.37
MAPT P10636 4/20 0.36
KDM4E B2RXH2 4/20 0.36
ALDH1A1 P00352 4/20 0.36
HSD17B10 Q99714 4/20 0.36
HPGD P15428 3/20 0.36
GAA P10253 2/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
TSHR P16473 2/20 0.36
MAPK1 P28482 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
TP53 P04637 1/20 0.36
NFKB1 P19838 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
SLC6A3 Q01959 1/20 0.36
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenanthrene SCHEMBL27796908 0.87 CYP2A6 (0.48) ALDH1A1HSD17B10TSHRTDP1L3MBTL1
1-Naphthol SCHEMBL27709868 0.83 CYP1A2 (0.57) MAPTKDM4EHSD17B10HPGDGAA
Naphthalene SCHEMBL27561595 0.82 CYP2A6 (0.38) CYP2A6
Triphenylene SCHEMBL5429154 0.82 KDM4E (0.30) MAPTKDM4EALDH1A1HSD17B10HPGD
Fluoranthene SCHEMBL27912222 0.82 ALDH1A1 (0.54) MAPTKDM4EALDH1A1HSD17B10HPGD
Anthracene SCHEMBL27342982 0.79 ALDH1A1 (0.32) MAPTALDH1A1HSD17B10HPGDTDP1
Dibenzofuran SCHEMBL5315116 0.76 MAPT (0.43) MAPTKDM4EALDH1A1HSD17B10HPGD
Phthalazine SCHEMBL11775146 0.74
SCHEMBL3223859 0.73 KIF11 (0.36) KDM4EALDH1A1HSD17B10HPGDTSHR
SCHEMBL25302086 0.73 ALDH1A1 (0.59) NISCHMAPTKDM4EALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6808603-B1 RADIATING WITH POLARIZED LIGHT TO EXCITE STARTING MATERIAL; CONCENTRATING ENANTIOMORPHS OR DIASTEREOMERS; PHOTOCHEMICALLY REVERSIBLE JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2004-10-26 US disclosed