⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochlorthiazide SCHEMBL352730 | 0.92 | — | — | |
| Hydrochlorthiazide SCHEMBL1422022 | 0.90 | — | — | |
| Hydrochlorthiazide SCHEMBL353307 | 0.89 | FFAR3 (0.30) | — | |
| Hydrochlorthiazide SCHEMBL28250666 | 0.88 | — | — | |
| Hydrochlorthiazide SCHEMBL2496915 | 0.88 | — | — | |
| Hydrochlorthiazide SCHEMBL29079282 | 0.88 | — | — | |
| Oxalic Acid SCHEMBL15227008 | 0.87 | — | — | |
| Hydrochlorthiazide SCHEMBL27521699 | 0.86 | FFAR3 (0.32) | — | |
| Hydrochlorthiazide SCHEMBL2581931 | 0.85 | — | — | |
| Hydrochlorthiazide SCHEMBL11664008 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008091594-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-31 | — | — | WO | claimed |
| US-20060194849-A1 | Fungicidal composition and method for controlling plant diseases | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2006-08-31 | — | — | US | claimed |
| EP-1679003-A1 | BACTERICIDE COMPOSITION AND METHOD OF CONTROLLING PLANT DISEASE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2006-07-12 | — | — | EP | claimed |
| EP-1196402-A1 | METHOD FOR PRODUCING 4-CYANO-2-AMINOMETHYLTHIAZOL | BASF AKTIENGESELLSCHAFT (DE) | 2002-04-17 | — | — | EP | claimed |
| EP-1196401-A1 | METHOD FOR PRODUCING 2-AMINOMETHYL-4-CYANO-THIAZOL | BASF AKTIENGESELLSCHAFT (DE) | 2002-04-17 | — | — | EP | claimed |
| WO-2001007425-A1 | METHOD FOR PRODUCING 2-AMINOMETHYL-4-CYANO-THIAZOL | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-01 | — | — | WO | claimed |
| WO-2001007426-A1 | METHOD FOR PRODUCING 4-CYANO-2-AMINOMETHYLTHIAZOL | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-01 | — | — | WO | claimed |
| EP-1049683-A2 | ISOTHIAZOLE CARBOXYLIC ACID AMIDES AND THE APPLICATION THEREOF IN ORDER TO PROTECT PLANTS | BAYER AG (DE) | 2000-11-08 | — | — | EP | claimed |
| WO-1999024413-A2 | ISOTHIAZOLE CARBOXYLIC ACID AMIDES AND THE APPLICATION THEREOF IN ORDER TO PROTECT PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-05-20 | — | — | WO | claimed |
| EP-0419944-B1 | Oxazole and thiazole carboxylic acid amines | BASF AG (DE) | 1995-03-15 | — | — | EP | claimed |
| EP-0419944-A2 | Oxazole and thiazole carboxylic acid amines | BASF Aktiengesellschaft (DE) | 1991-04-03 | — | — | EP | claimed |
| US-12486289-B2 | Tricyclic compounds as glycogen synthase kinase 3 (GSK3) inhibitors and uses thereof | THE BROAD INSTITUTE, INC. (US) | 2025-12-02 | — | — | US | disclosed |
| CN-119638687-A | Aromatic heterocyclic pyrrolidones and uses thereof | 杭州百新生物医药科技有限公司 | 2025-03-18 | — | — | CN | disclosed |
| EP-3606528-B1 | TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF | BROAD INST INC (US) | 2023-10-18 | — | — | EP | disclosed |
| CN-110958882-B | Tricyclic compounds as glycogen synthase kinase 3 (GSK 3) inhibitors and uses thereof | 布罗德研究所股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| EP-0419944-A2 | Oxazole and thiazole carboxylic acid amines | BASF Aktiengesellschaft (DE) | 1991-04-03 | — | — | EP | disclosed |
| EP-0419944-A2 | Oxazole and thiazole carboxylic acid amines | BASF Aktiengesellschaft (DE) | 1991-04-03 | — | — | EP | disclosed |
| US-4987196-A | FROM NATURAL RUBBER LATEX | THE YOKOHAMA RUBBER CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| EP-0335831-A1 | Thiazole-5-carboxylic acid amides for protecting cultivated plants against the phytotoxic activity of highly active herbicides | CIBA-GEIGY AG (CH) | 1989-10-04 | — | — | EP | disclosed |
| US-3825552-A | THIAZOLE CARBAMATE PESTICIDES | E.I. DU PONT DE NEMOURS AND COMPANY | 1974-07-23 | — | — | US | disclosed |