Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7731889 | 0.91 | ELANE (0.37) | ELANEPLCG1L3MBTL1HTR2A | |
| SCHEMBL7722340 | 0.90 | ELANE (0.41) | ELANEPLCG1L3MBTL1HTR2A | |
| SCHEMBL7722386 | 0.89 | L3MBTL1 (0.40) | ELANEPLCG1L3MBTL1HTR2A | |
| SCHEMBL7722347 | 0.88 | ELANE (0.35) | ELANEPLCG1L3MBTL1HTR2A | |
| SCHEMBL7732306 | 0.87 | PLCG1 (0.35) | ELANEPLCG1L3MBTL1HTR2A | |
| SCHEMBL7728033 | 0.86 | ELANE (0.38) | ELANEPLCG1L3MBTL1HTR2A | |
| SCHEMBL6622725 | 0.85 | CACNA1C (0.34) | — | |
| SCHEMBL7731948 | 0.85 | PLCG1 (0.34) | ELANEPLCG1L3MBTL1HTR2A | |
| SCHEMBL7729532 | 0.85 | ELANE (0.35) | ELANEPLCG1L3MBTL1HTR2A | |
| SCHEMBL6770987 | 0.84 | DPP8 (0.33) | ELANEPLCG1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825187-B2 | CARBAPENEM DERIVATIVES SUBSTITUTED AT THE 2-POSITION WITH A SUBSTITUTED IMIDAZO(5,1-B)THIAZOLE GROUP; USE AGAINST ANTIBIOTIC RESISTANT STAPHYLOCOCCUS AUREUS AND PSEUDOMONAS AERUGINOSA, ENTEROCOCCI AND INFLUENZA VIRUS | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-11-30 | — | — | US | disclosed |