Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6771567 | 0.82 | ITK (0.50) | ITKINSR | |
| SCHEMBL6469125 | 0.77 | ITK (0.77) | ITKINSR | |
| SCHEMBL6632540 | 0.76 | ITK (0.72) | ITKINSR | |
| SCHEMBL6772813 | 0.73 | ITK (0.69) | ITKINSR | |
| SCHEMBL6469039 | 0.72 | ITK (0.74) | ITKINSR | |
| SCHEMBL9669380 | 0.72 | LMNA (0.47) | — | |
| SCHEMBL25123079 | 0.71 | SMN1; SMN2 (0.76) | — | |
| SCHEMBL4522241 | 0.71 | SMN1; SMN2 (0.76) | — | |
| SCHEMBL8395225 | 0.71 | SMN1; SMN2 (0.76) | — | |
| SCHEMBL6469021 | 0.71 | ITK (0.74) | ITKINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825219-B2 | NITROGEN COMPOUNDS SUCH AS 4-((5-(CYCLOHEXYL-METHYL-CARBAMOYL) -2(THIOPHENE-2-CARBONYL)-AMINO)BENZIMIDAZOL-1-YL)-BUTYRIC ACID ADMINISTERED FOR THE PROPHYLAXIS OF INFLAMMATORY, IMMUNOLOGICAL AND ALLERGIC DISORDERS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2004-11-30 | — | — | US | disclosed |
| US-20030144281-A1 | Substituted benzimidazole compounds | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2003-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144281-A1 | Substituted benzimidazole compounds | HRH2, HRH4, HRH1 | ITK 1721/4885INSR 2096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.