Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.46 |
| ▸ | ITGAV | P06756 | 8/20 | 0.46 |
| ▸ | CTSS | P25774 | 7/20 | 0.39 |
| ▸ | CTSL | P07711 | 6/20 | 0.39 |
| ▸ | CTSK | P43235 | 6/20 | 0.39 |
| ▸ | CTSB | P07858 | 5/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6771856 | 0.80 | ALDH1A1 (0.46) | ITGB3ITGAVNAMPTDHODH | |
| SCHEMBL5878414 | 0.79 | ITGB3 (0.62) | ITGB3ITGAVCTSSCTSLCTSK | |
| SCHEMBL5878410 | 0.79 | ITGB3 (0.62) | ITGB3ITGAVCTSSCTSLCTSK | |
| SCHEMBL5878211 | 0.77 | ITGB3 (0.77) | ITGB3ITGAV | |
| SCHEMBL5878214 | 0.77 | ITGB3 (0.77) | ITGB3ITGAV | |
| SCHEMBL6773278 | 0.71 | ALDH1A1 (0.55) | — | |
| SCHEMBL6773280 | 0.71 | ALDH1A1 (0.55) | — | |
| SCHEMBL5878520 | 0.69 | ITGB3 (0.53) | ITGB3ITGAV | |
| SCHEMBL10767753 | 0.67 | MAPT (0.47) | ITGB3NAMPT | |
| SCHEMBL5878292 | 0.67 | ITGB3 (0.62) | ITGB3ITGAVCTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677360-B2 | TREATMENT AND PROPHYLAXIS OF CANCER, ARTERIOSCLEROSIS, RESTENOSIS, OSTEOPOROSIS AND EYE DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-01-13 | — | — | US | disclosed |